A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study
Son Da-Hye, 유수현, 사호석, 조경자,
소속 상세정보
( Son Da-Hye )
University of Ulsan College of Medicine Asan Medical Center Department of Pathology
유수현 ( Yoo Su-Hyun )
University of Ulsan College of Medicine Asan Medical Center Department of Pathology
사호석 ( Sa Ho-Seok )
University of Ulsan College of Medicine Asan Medical Center Department of Ophthalmology
조경자 ( Cho Kyung-Ja )
University of Ulsan College of Medicine Asan Medical Center Department of Pathology
KMID : 0357920130470020158
Abstract
Orbital solitary fibrous tumor (SFT) has recently been proposed as the encompassing terminology for hemangiopericytoma, giant cell angiofibroma (GCAF), and fibrous histiocytoma of the orbit. The lacrimal gland is a very rare location for both SFT and GCAF. A 39-year-old man presented with a painless left upper eyelid mass. An orbital computed tomography scan identified a 1.1 cmsized well-defined nodule located in the left lacrimal gland. He underwent a mass excision. Histopathologic examination showed a proliferation of relatively uniform spindle cells with a patternless or focally storiform pattern. Dilated vessels were prominent, but angiectoid spaces lined with giant cells were absent. Floret-type giant cells were mostly scattered in the periphery. The tumor was immunoreactive for CD34 and CD99, but negative for smooth muscle actin and S-100 protein. This is the first Korean case of SFT of the lacrimal gland with overlapping features of GCAF, suggesting a close relationship between the two entities.
키워드
Solitary fibrous tumors; Giant cells; Lacrimal apparatus; Orbit
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