Rhabdoid Colorectal Carcinomas: Reports of Two Cases
이상화, 설혜실, 김욱연, 임소덕, 김완섭, 황태숙, 한혜승,
소속 상세정보
이상화 ( Lee Sang-Hwa )
Aerospace Medical Center Research Center Department of Pathology
설혜실 ( Seol Hye-Sil )
Konkuk University School of Medicine Department of Pathology
김욱연 ( Kim Wook-Youn )
Konkuk University School of Medicine Department of Pathology
임소덕 ( Lim So-Dug )
Konkuk University School of Medicine Department of Pathology
김완섭 ( Kim Wan-Seop )
Konkuk University School of Medicine Department of Pathology
황태숙 ( Hwang Tae-Sook )
Konkuk University School of Medicine Department of Pathology
한혜승 ( Han Hye-Seung )
Konkuk University School of Medicine Department of Pathology
KMID : 0357920130470040372
Abstract
Rhabdoid colorectal carcinomas are very rare and only 10 cases have been previously reported. We report two cases of rhabdoid colorectal carcinoma, one arising in the sigmoid colon of a 62-year-old man and another in the rectum of an 83-year-old woman. In both cases, the patients had advanced tumors with lymph node metastases. The tumors mostly showed a diffuse arrangement with rhabdoid features and small glandular regions were combined. Transitional areas from the adenocarcinomas to the rhabdoid tumors were also noted. Adenocarcinoma cells were positive for mixed cytokeratin (CK), CK20 and epithelial membranous antigen (EMA), but focal positive for vimentin. The rhabdoid tumor cells were positive for mixed CK, but focal positive or negative for CK20 and EMA. In addition, they were diffusely positive for vimentin, but negative for desmin. The histological and immunohistologial findings of these two cases suggest that the rhabodid tumor cells originated from dedifferentiated adenocarcinomas.
키워드
Adenocarcinoma; Colon; Rectum; Rhabdoid tumor
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