Sebaceous Carcinoma Arising in Mature Cystic Teratoma of Ovary
An Hyo-Jeong, 정용한, 윤혜경, 정수진,
소속 상세정보
( An Hyo-Jeong )
Inje University Busan Paik Hospital Department of Pathology
정용한 ( Jung Yong-Han )
Inje University Busan Paik Hospital Department of Pathology
윤혜경 ( Yoon Hye-Kyoung )
Inje University Busan Paik Hospital Department of Pathology
정수진 ( Jung Soo-Jin )
Inje University Busan Paik Hospital Department of Pathology
KMID : 0357920130470040383
Abstract
Roughly 1% of mature cystic teratomas undergo malignant transformation. In particular, cutaneous- type adnexal neoplasms may occur in mature cystic teratomas. Sebaceous carcinomas, which arise from mature cystic teratomas, have rarely been observed, with only seven cases previously reported. Here, we present a case of a 69-year-old female who had pelvic pain for two weeks and who subsequently underwent bilateral salpingo-oophorectomy and hysterectomy. Her left ovary showed a unilocular cyst, measuring 22.0 cm in diameter, filled with sebaceous material and a few hairs. A luminally-protruding solid mass measuring 4.0 cm in diameter was also noted. Microscopic findings revealed lobular or diffusely arranged basophilic, atypical sebaceous cells connected to a typical mature cystic teratoma. Tumor cells demonstrated positive immunoreactivity for high molecular weight cytokeratin, cytokeratin 7, cytokeratin 19, epithelial membrane antigen, and carcinoembryonic antigen. Here, we present a case of sebaceous carcinoma arising from a mature cystic teratoma along with a review of previously published reports.
키워드
Sebaceous carcinoma; Sebaceous adenoma; Mature cystic teratoma; Ovary
원문 및 링크아웃 정보
등재저널 정보