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Spindle Cell Rhabdomyosacoma of Uterus: A Case Study

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±è´ë¿î ( Kim Dae-Woon ) 
Eulji University School of Medicine Department of Obstetrics and Gynecology

½ÅÁ¤È¯ ( Shin Jung-Hwan ) 
Eulji University School of Medicine Department of Obstetrics and Gynecology
ÀÌÈ£Á¤ ( Lee Ho-Jung ) 
Eulji University School of Medicine Department of Pathology
È«¿µ¿Á ( Hong Young-Ok ) 
Eulji University School of Medicine Department of Pathology
ÁÖÁ¾Àº ( Joo Jong-Eun ) 
Eulji University School of Medicine Department of Pathology
±èÀº°æ ( Kim Eun-Kyung ) 
Eulji University School of Medicine Department of Pathology

Abstract


Uterine rhabdomyosarcoma (RMS) typically presents as a mixed epithelial and mesenchymal tumors. Pure RMSs of the female genital tract are uncommon. Spindle cell variant of RMS is a rare morphologic subtype of embryonal RMS and mostly occurs in the paratesticular region of children. Here, we present a case of uterine spindle cell RMS in a 76-year-old woman. The tumor, 20¡¿15¡¿7 cm in size, was highly necrotic and adherent to the colon and rectum. Tumor cells were mostly spindle-shaped, and isolated rhabdomyoblasts were scattered. Immunohistochemical stains for myoglobin and myo-D1 showed diffuse positivity for tumor cells. The patient died only of disease three months after diagnosis.

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Rhabdomyosarcoma; Spindle cell variant; Uterus

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