Large Cell Calcifying Sertoli Cell Tumor of the Testis: A Case Study and Review of the Literature
송대현, 정성묵, 박종탁, 윤각원, 김병권, 이종실,
소속 상세정보
송대현 ( Song Dae-Hyun )
Armed Forces Capital Hospital Department of Pathology
정성묵 ( Jeong Seong-Muk )
Armed Forces Capital Hospital Department of Pathology
박종탁 ( Park Jong-Tak )
Armed Forces Capital Hospital Department of Urology
윤각원 ( Yun Gak-Won )
Armed Forces Capital Hospital Department of Internal Medicine
김병권 ( Kim Byoung-Kwon )
Green Cross Reference Laboratory Department of Pathology and Human Genome Research Institute
이종실 ( Lee Jong-Sil )
Gyeongsang National University School of Medicine Department of Pathology
KMID : 0357920140480010050
Abstract
A 24-year-old man was admitted due to an incidentally detected mass in his left testis, which showed radiopaque calcification on plain X-ray film. Left orchiectomy was performed, and the resected testis contained a well-demarcated, hard mass measuring 1.1 cm. Histological analysis revealed that the tumor was composed of neoplastic cells, fibrotic stroma, and laminated or irregularly shaped calcific bodies. The individual cells had abundant eosinophilic or clear cytoplasm with round nuclei, each of which contained one or two conspicuous nucleoli. They were arranged in cords, trabeculae, clusters, and diffuse sheets. There were several foci of intra-tubular growth patterns, with thickening of the basal lamina. Immunohistochemically, the neoplastic cells were positive for S-100 protein and vimentin, focally positive for inhibin alpha, and negative for cytokeratin, CD10, and Melan-A. In addition to reporting this rare case, we also review the relevant literature regarding large cell calcifying Sertoli cell tumors.
키워드
Testis; Sertoli cell tumor; Immunohistochemistry
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