A Case of Mixed Adenoneuroendocrine Carcinoma of the Common Bile Duct: Initially Diagnosed as Cholangiocarcinoma
이순욱, 이인석, 조유경, 박재명, 김상우, 최명규, 이명아, 홍태호, 유영경, 정은선,
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이순욱 ( Lee Soon-Wook )
Catholic University Seoul St. Mary’s Hospital Department of Internal Medicine
이인석 ( Lee In-Seok )
Catholic University Seoul St. Mary’s Hospital Department of Internal Medicine
조유경 ( Cho Yu-Kyung )
Catholic University Seoul St. Mary’s Hospital Department of Internal Medicine
박재명 ( Park Jae-Myung )
Catholic University Seoul St. Mary’s Hospital Department of Internal Medicine
김상우 ( Kim Sang-Woo )
Catholic University Seoul St. Mary’s Hospital Department of Internal Medicine
최명규 ( Choi Myung-Gyu )
Catholic University Seoul St. Mary’s Hospital Department of Internal Medicine
이명아 ( Lee Myung-Ah )
Catholic University Seoul St. Mary’s Hospital Department of Internal Medicine
홍태호 ( Hong Tae-Ho )
Catholic University Seoul St. Mary’s Hospital Department of Surgery
유영경 ( You Young-Kyoung )
Catholic University Seoul St. Mary’s Hospital Department of Surgery
정은선 ( Jung Eun-Sun )
Catholic University Seoul St. Mary’s Hospital Department of Pathology
KMID : 0357920140480060445
Abstract
Neuroendocrine tumors (NETs) are mostly found in the gastrointestinal tract and the pancreas. The World Health Organization (WHO) classification (2010) has been widely used to categorize NETs.1 In the digestive system, NETs including those found within the bile ducts, are classed as NET G1 (carcinoid, mitotic count of <2 per 10 high-power fields (HPF) and/or ≤2% Ki-67 index), NET G2 (mitotic count 2?20 per 10 HPF and/or 3%?20% Ki-67 index), NET G3 (neuroendocrine carcinoma, mitotic count of >20 per 10 HPF and/or >20% Ki-67 index), and mixed adenoneuroendocrine carcinoma (MANEC).1 NETs arising from the bile duct are rare, accounting for only 1.8% of gastroenteropancreatic NETs.2 MANECs of the common bile ducts (CBDs) are extremely rare, and only a few cases have been reported thus far.3-5
In this study, we report a case of MANEC arising from themid CBD.
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