간손상이 생식선에 미치는 영향. 제2편:간손상이 웅백서 생식선에 대한 성Hormone 투여효과에 미치는 영향
Influence of Hepatic Damage on the Male Reproductive Glands : II. Influence of Hepatic Damage on the Effect of Exogenous Sex Hormones on the Reproductive Glands of White Rats
소속 상세정보
김영균/Kim YK
이학송/Lee HS
KMID : 0358319600010020097
Abstract
Young adults male rats were injected with carbon tetrachloride to induce damage to the liver in order to study the influence of this damage on the effects of exogenous estrogens and androgens on the reproductive glands and their accessories. The liver damage by the toxin caused a marked decrease in the weights of the prostate and the seminal vesicles of the rat whereas there was no great alteration in testicular effect of exogenous androgen seemed not be significant whereas the effect of exogenous estrogen was greatly increased by the condition. Histological findings in the reproductive glands following hepatic damage are chiefly those of atrophic changes. Citric acid concentration in the prostatic tissue was not influenced by liver damage but estrogen administration caused a marked increase and estrogen with liver damage caused a sharper rise in the concentration. Citric acid content of prostatic tissue can not be taken as an index of androgenic activity.
키워드
간손상; 내분비학; 성호르몬; liver cirrhosis; citric acid; exogenous sex hormon
원문 및 링크아웃 정보
등재저널 정보