간손상이 생식선에 미치는 영향. 제4편:간손상을 입은 웅백서 생식선에 대한 Cortisone의 효과
Influence of Hepatic Damage on the Male Reproductive Glands : IV. Effect of Cortisone on the Reproductive Glands of Male White Rats with Liver Damage
소속 상세정보
김영균/Kim YK
이학송/Lee HS
KMID : 0358319600010020111
Abstract
Young adult male rats were injected with carbon tetrachloride along with cortisone acetate simultaneously and the effect of cortisone acetate on the damage of the liver and the liver´s effect on the reproductive gland and its accessories were studied. The following results were obtained : Cortisone acetate given rats with damaged livers caused a very remarkable decrease in the weights of the accessory glands of reproduction, while the liver was restored to normal hepatic architecture. Judging from the marked weight decreases of the glands, cortisone acetate is thought to be responsible for enhancing the estrogenic effect through liver dysfunction despite the return to normal hepatic histology. Citric acid concentration in the prostatic tissue was not altered greatly by cortisone acetate administration. The concentration of the prostatic citrate can not be taken as an index of androgenic activity.
키워드
간손상; 내분비학; 코티손; liver cirrhosis; cortisone; male reproductive glan
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