요로결석환자의 혈중 및 요중 요산변동에 관한 임상적 관찰
Study on Serum and Urinary Uric Acid Level in Patients with Urinary Stone
소속 상세정보
정용원/Chung YW
김태진/Kim TC
KMID : 0358319820230050629
Abstract
Currently, uric acid disorders, especially including hyperuricosuria, are thought to be important in the formation Of idiopathic calcium urolithiasis.
Herein, we estimated the serum concentration and urinary excretion of uric acid in I22 stone-formers, comparing to those in 56 controls. Also, various theories about the pathogenesis of uric acid disorder and stone formation were discussed.
The results were as follows:
1. Serum uric acid levels of stone-formers were significantly higher than those of controls, in total and female, but, not in male.
2. Urinary uric acid levels of stone-formers were significantly higher than those of controls in total, male and female.
3. Hyperuricemia was significantly more frequent for stone-formers in total, male and female.
4. Hyperuricosuria was significantly more frequent for stone-formers in total, but, not significantly more frequent for stone-formers in male and female.
5. The incidence of stone-formers, in whom hyperuricemia and hyperuricosuria were not present at the sometime, was significantly less than that Of controls.
These results suggest the possibility that uric acid disorder may play some roles in the genesis of urinary stone.
키워드
요로결석; 혈중및요중요산; serum; urinary uric acid level; urinary stone
원문 및 링크아웃 정보
등재저널 정보