CISCA Regimen으로 치료한 진행된 방광암 2례
Two Cases of Advanced Bladder Carcinoma, Treated with CISCA Regimen
소속 상세정보
홍성준/Hong SJ
김천일/이진무/Kim CI/Lee JM
KMID : 0358319860270010191
Abstract
The CISCA regimen (Cis-platinum, Cyclophosphamide and Adriamycin combination), first reported by Sternberg et al. at 1977 is most excellent combination chemotherapy regimen for treatment of advanced bladder carcinoma other than single or combination chemotherapy regimen ever reported and its overall response rate was average 46%.
We experienced two cases of advanced bladder carcinoma, treated with CISCA regimen, followed by radiotherapy and/or cystectomy. All 3 drugs (70mg/m2 Cis-platinum in five divided dose, 400mg/m2 Cyclophosphamide and 40mg/m2 Adriamycin) were given as a single dose every 1 weeks. During enforcement of each 3 and 2 cycles, the definite symptomatic relief was observed. The complications were minimal and were relatively well tolerated by patients. The chemotherapy of transitional cell carcinoma of the bladder with CISCA regimen appears to be effective.
키워드
방광종양; 화학요법; bladder tumor; CISCA
원문 및 링크아웃 정보
등재저널 정보