Bethanechol chloride가 가토의 방광경부의 수축에 미치는 영향
Effect of Bethanechol Chloride on Rabbit Bladder Neck Contractility: In-Vitro Study
김광명, 김건석, 최황,
소속 상세정보
김광명 ( )
고려대학교
김건석 ( )
고려대학교
최황 ( )
고려대학교
KMID : 0358319920330020294
Abstract
Bethanechol promotes bladder emptying by acting on postganglionic parasympathetic effector cells within detrusor muscle to elicit a contraction and is widely used to enhance bladder emptying for incomplete lower motor neuron lesion, idiopathic
hypotonic
bladder and postoperative urinary retention. However its effects on bladder outlet is inconclusive. Therefore, in vitro study for the effects of bethanechol on the muscle strip from the rabbit bladder neck were undertaken. Ten male white rabbit
bladders
were divided into body, base and neck and contractile responses of three strips were done. Bethanechol chloride produces most potent contractile response on the bladder body and comparatively less on the bladder base and bladder neck in a
dose-dependant
manner.
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