결석환자에서 24시간뇨의 대사검사에 대한 평가
Biochemical Evaluation of 24-hour urine in Stone Patients
선판일, 조태형, 장대수,
소속 상세정보
선판일 ( Sun Pan-Yil )
조선대학교
조태형 ( )
조선대학교
장대수 ( )
조선대학교
KMID : 0358319930340061016
Abstract
The fifty four patients with urinary stones (38 men, 16 women) and nine controls on usual constant diet were evaluated with the measurement of urinary minerals, electrolytes, citrate and calculation of net gastrointestinal absorption of alkali by
recently devised simple method, i.e., (Na+K+Ca+Mg)-(Cl+1.8P) of urine, to evaluate between citraturia and net gastrointestinal absorption of alkali. In 24-hour urine measurement, the stone patients in comparison with controls showed
hyperexcretion
of
calcium(p<0.05), oxalate(p<0.05) and sodium(p<0.05) and hypoexcretion of phosphorus (p<0.05), potassijum(p<0.001) and citrate(p<0.05). Hypocitraturia (less than 320mg/dl) was noted in 64.8% of all stone patients though mean urine citrate levels
were
higher in women compared to men without stastistical significance. In view of gender difference, all 24-hour urine analysis except citrate in stone patients were higher in men than women, of which calcium, creatinine, potassium and chloride were
statistcally significant(p<0.05). A retrograde analysis between citraturia and net gastrointestinal absorption of alkali in both stone patients and controls didn't reveal any significant correlation. In conclusion, 24-hour urine biochemistries
are
an
influential factor of the stone formation and this study regarding to relation between hypocitraturia and reduced net gastrointestinal absorption of alkali shows no correlation.
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