¿ªÀü»çÁßÇÕÈ¿¼Ò¿¬¼â¹ÝÀÀÀ» ÀÌ¿ëÇÑ ÀÎü ½Å¼¼Æ÷¾Ï ¤ÄÆ÷¤Ì¿¡¼ÀÇ Interleukin-4 Receptor ¹ßÇö¿¡ °üÇÑ ¿¬±¸
Interleukin-4 Receptor Expression on Human Renal Cell Carcinoma Cell Lines by a Reverse Transcription-Polymerase Chain Reaction
¼Ò¼Ó »ó¼¼Á¤º¸
õÁØ
Á¤µ¿ÁØ/ÃÖÁ¾º¸/°í¼º°Ç/¼ÕÁ¤¿ø
KMID : 0358319950360020121
Abstract
Recently interleukin-4 (IL-4) has been suggested to be a promising therapeutic agent for the maligneant tumors of both murine and human origin. The effect of IL-4 is mediated by IL-4 receptor (IL-4R), which has been shown to be expressed in may
normal
and tumor cell lines. We herein tested two cell lines of human renal cell carcinoma (RCC), Caki-1 and CURC-II, for the expression of IL-4R gene. On the reverse transcritpion-polymerase chain reaction study, both cell lines expressed IL-4R mRNA.
The
present study suggests that it would be worthwhile to investigate the anti-tumor effect of IL-4 on Caki-1 and CURC-II, which may help to develop new therapeutic strategies for RCC using IL-4.
Å°¿öµå
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸