배뇨증상을 동반한 비전립선암 환자에서 연령에 따른 전립선 특이항원의 상한치
Upper Limits for PSA in Relation to Age in Clinically Prostatic Cancer-free Patients with voiding Symptoms
이창우, 김덕배,
소속 상세정보
이창우 ( )
충남대학교 가정대학 가정교육과
김덕배 ( )
Chungbuk National University
KMID : 0358319950360060609
Abstract
We measured the concentration of serm PSA to define statistical upper limits for Psa in relation to age in 228 men without clinical evidence of prostatic cancer. We defined the cancer-free group as men with a PSA less than or equal to 2.5ng/ml
(ELSA-PSAR monoclonal immunoradiometric assay) and nonsuspicious digital rectal examination and those with an abnormality in either parameter underwent transrectal ultrasound and pathologically excluded prostatic cancer from the group by
transrectal
prostatic biopsy transurethral resection.
A total 252 men between 40 and 79 years of age entered the protocol, of whom 228 men satisfied our cancer-free criteria. There was a significant correlation between natural logarithm transformed PSA (In PSA) and age by linear regression analysis
(r=0.32, p=0.02) and age-specific uppe rlimits of Psa (mean+2SD) were 2.62ng/ml in the 40 to 49-year group, 3.45ng/ml in the 50 to 59-year group, 5.09ng/ml in 60 to 69-ye4ar group and 7.07ng/ml in the 70 to 79-year group.
키워드
원문 및 링크아웃 정보
등재저널 정보