만성 비세균성 전립선염 환자의 정자운동성에 대한 연구-항정자항체와 정장액 cytokine 및 정장액성분과의 상관관계-
Sperm Motility in Chronic Nonbacterial Prostatitis-Related to Antisperm Antibody and Seminal Cytokine and Seminal Plasma Composition-
양구현, 송윤섭, 최용섭, 정희,
소속 상세정보
양구현 ( )
연세대학교
송윤섭 ( )
연세대학교
최용섭 ( )
연세대학교
정희 ( )
연세대학교
KMID : 0358319960370040433
Abstract
Seminal inflammatory white blood cells in patients with chronic nonbacterial prostatitis may be related to the decrease of semen quality affecting fertility. So we evaluated the change of sperm motility, the levels of antisperm antibodies, the
seminal
levels of various cytokines and the change of seminal biochemical compositions that may affect sperm motility in the control group. We also examined chronic nonbacterial prostatitis with pyospermia to establish the role of seminal inflammatory
white
blood cells on on alteration of sperm motility. The relation between various affecting factors and sperm motility were also evaluated. Titers of antisperm antibodies were low in patients with chronic nonbacterial prosttatitis. Interleukin-1αand
interleukin-8 of seminal inflammatory cytokines were present in increased quantities in patients with chronic nonbacterial prostatitis and interleukin-8 of these increases were correlated to sperm motility. Among the seminal composition, the
level
of
zinc was decreased significnatly which was not corrrelated to sperm motility. In conclusion, sperm motility was decreased and alterat8ion in interleukin-8 of seminal cytokines were correlated with sperm motility in chronic nonbacterial
prostatitis.
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