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Effect of Estrogen on the Urinary Symptoms and Urodynamic Parameters in Postmenopausal Women
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KMID : 0358319960370111273
Abstract
Effects of oral estrogen (Tibolone) on the urinary symptoms and urodynamics parameters were assessed by a double-blind prospective trial in 24 postmenopausal women. Patients were assessed subjectively and objectively before and after treatment by
symptom score chart, urethral pressure profiles and uroflow. There was statistical difference in the subjective response (symptom score) to treatment between the two groups (p<0.001), there was no significant urodynamic changes (p>0.05). Although
there
was no significant urodynamic changes, estrogen treatment in postmenopausal women was effective to improve urinary symptoms. Careful observation with periodic follow up will be needed because of possible harmful side effects of estrogen.
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