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Àü¸³¼± ºñ´ëÁõ ȯÀÚ¿¡¼­ ÀÓ»óÁõ»ó, °æÁ÷Àå ÃÊÀ½ÆÄ·Î ÃøÁ¤ÇÑ Total Prostate Volume, Transitional Zone Volume ¹× Ç÷û PSA¿ÍÀÇ »ó°ü °ü°è¿¡ °üÇÑ ¿¬±¸ A Study of Correlations among International Prostate Symptom Score (IPSS), Volume of Total and Transition Zone of Prostate Measured by Transrectal Ultrasonography, Serum PSA Level in Benign Prostatic Hyperplasia

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¾çÀçÁØ/Jae Jun Yang ±è¼±Áø/½Å±â¿ë/¹ÚÇØ¿µ/±è¿ë¼ö/ÀÌÃá¿ë/Sun Jin Kim/Ki Yong Shin/Hae Young Park/Yong Su Kim/Tchun Yong Lee

Abstract

°á·Ð
ÀúÀÚµéÀº 1995³â 10¿ùºÎÅÍ 1996³â 8¿ù±îÁö Àü¸³¼± ºñ´ëÁõÀ¸·Î Áø´ÜµÇ°í Ä¡·á¹ÞÀº 42¸íÀÇ
ȯÀÚ¸¦ ´ë»óÀ¸·Î ÇÏ¿© TRUS·Î ÃøÁ¤ÇÑ Àü¸³¼± Àüüũ±â, Àüȯ´ëÀÇ Å©±â, Ç÷û PSA ¹×
IPSS¿¡ ÀÇÇÑ ÀÓ»óÁõ»ó Á¡¼ö¿ÍÀÇ »ó°ü°ü°è¸¦ ºÐ¼®ÇÏ¿© ´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù.
ù°, Àü¸³¼± ºñ´ëÁõ ȯÀÚ¿¡¼­ IPSS¿¡ ÀÇÇÑ ÀÓ»óÁõ»óÁ¡¼ö´Â Àü¸³¼± ÀüüÀÇ Å©±â, Àüȯ´ë
ÀÇ Å©±â, transition zone index ¹× Ç÷û PSA¼öÄ¡¿Íµµ »ó°ü°ü°è°¡ ¾ø´Â °ÍÀ¸·Î ºÐ¼®µÇ¾ú´Ù.
µÑ°, Àü¸³¼± ºñ´ëÁõ ȯÀÚ¿¡¼­ Ç÷û PSA¼öÄ¡, Àü¸³¼±ÀÇ Àüüũ±â, Àüȯ´ëÀÇ Å©±â,
transition zone index °£¿¡´Â Åë°èÇÐÀûÀ¸·Î À¯ÀÇÇÑ ¾çÀÇ »ó°ü°ü°è°¡ ÀÖ´Â °ÍÀ¸·Î °üÂûµÇ¾ú
´Ù.
ÀÌ»óÀÇ °á°ú·Î ÇöÀçÀÇ IPSS¿¡ ÀÇÇÑ ÀÓ»óÁ¡¼ö´Â Àü¸³¼± ºñ´ëÁõ ȯÀÚÀÇ ¿©·¯ °¡Áö ÀÓ»óÁõ
»óÀ» ºñ±³Àû Àß Ç¥ÇöÇØ ÁÖ°í ÀÖÀ¸³ª, Àü¸³¼± ºñ´ëÁõ ȯÀÚ¿¡¼­ ȯÀÚÀÇ Áõ»óÁ¤µµ ¹× Àü¸³¼±ÀÇ
¿©·¯ °¡Áö ÀÓ»óÀû ôµµ¸¦ ¹Ý¿µÇÏ´Â ÁöÇ¥¸¦ ±¸Çϱâ À§Çؼ­´Â º¸´Ù °´°üÀûÀÎ Áõ»ó Á¡¼ö »êÁ¤
ü°èÀÇ °³¹ßÀ» Æ÷ÇÔÇÏ¿© º¸´Ù ¸¹Àº ¼öÀÇ È¯ÀÚ¸¦ ´ë»óÀ¸·Î ÇÑ ÀüÇâÀûÀÎ ¿¬±¸°¡ ÀÌ·ç¾îÁ®¾ß
ÇÒ °ÍÀ¸·Î »ç·áµÈ´Ù.
#ÃÊ·Ï#
This study was aimed to investigate the possible correlations between International
Prostate Symptom Score (IPSS), volume of total and transition zone of prostate, and
serum prostate specific antigen (PSA) level in 42 patients diagnosed and treated as
benign prostatic hyperplasia. We got IPSS by interview and calculated the volume of the
total and the transition zone (TZ vol) of prostate by transrectal ultrasonography. The
size of the total prostate was 37.35¡¾12.9 cc (mean¡¾standard deviation) and that of the
transition zone was 17.72 ¡¾ 10.04 cc. Transition zone index(transition zone volume/total
prostate volume, TZ index) was calculated and its value was 0.45 ¡¾ 0.14. Symptom
score was not correlated with total prostate volume, TZ volume or 72 index (r=0.27,
p>0.05; r=0.23, p>0.05; r=0.16, p>0.05, respectively). Either it did not show correlation
with serum PSA level (r=0.16, p>0.05).
However, there were statistically significant correlations among serum PSA, total
volume, TZ volume, TZ index (r=0.66, p<0.05; r=0.64, p<0.05; r=0.47, p<0.05).
From these results, it is difficult to find significant correlations between symptom
severity easured by IPSS and several clinical indices such as total prostate volume,
transitional volume, TZ index or serum PSA level. Prospective study including
developing a more objective symptom scoring system is needed to get a more useful
clinical index reflecting the symptom severity of the BPH patients as well as clinical
status of them.

Å°¿öµå

Prostate; Transition zone volume; PSA; International prostate symptom score; BPH;

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