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³²¼ººÒÀÓȯÀÚÀÇ Ç÷Àå°ú Á¤Àå³» Zinc¿Í SeleniumÄ¡ÀÇ ÀÇÀÇ Significance of Zn and Se Levels in Seminal Plasma and Blood Plasma in Male Infertile Patients

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Abstract

°á·Ð
ºÎ»ê´ëÇб³º´¿ø ºñ´¢±â°ú¸¦ ³»¿øÇÑ ³²¼º ºÒÀÓȯÀÚ¿¡¼­ Ç÷Àå°ú Á¤Àå¾×³» Zn¹× SeÀÌ °íȯ
ÀÇ Á¶Á¤±â´É°ú Á¤ÀÚÀÇ ±â´ÉÀå¾Ö¸¦ À¯¹ßÇÒ ¼ö ÀÖ´Â ÀÓ»óÀû ÁöÇ¥·Î ÀÌ¿ëÇÒ ¼ö ÀÖ´ÂÁö¸¦ ¾Ë¾Æ
º¸°íÀÚ ³²¼º ºÒÀÓÀ» ÁÖ¼Ò·Î ³»¿øÇÑ 60¸íÀÇ ³²¼º ºÒÀÓȯÀÚ¿Í 10¸íÀÇ Á¤»ó ´ëÁ¶±º¿¡¼­ Ç÷Àå°ú
Á¤Àå¾×³» Zn, SeÀ» ÃøÁ¤ ºñ±³ÇÏ¿© ´ÙÀ½°ú °°Àº ¼ºÀûÀ» ¾ò¾ú´Ù.
1. ´ëÁ¶±º¿¡¼­ ZnÀÌ Á¤Àå¾×¿¡¼­ Ç÷À庸´Ù À¯ÀÇÇÏ°Ô ³ô¾Ò°í (p<0.05), SeÀº Ç÷Àå¿¡¼­ Á¤Àå
¾×º¸´Ù À¯ÀÇÇÏ°Ô ³ô¾Ò´Ù (p<0.05).
2. ºÒÀÓ±ºÀÇ Ç÷Àå¿¡¼­ ZnÀº ´ëÁ¶±ºº¸´Ù ³·¾ÒÀ¸³ª Åë°èÇÐÀû À¯ÀǼºÀº ¾ø¾ú°í (p>0.05), Se
Àº ¾ç±º¿¡¼­ ºñ½ÁÇÏ°Ô ÃøÁ¤µÇ¾ú´Ù.
3. ºÒÀÓ±ºÀÇ Á¤Àå¾×¿¡¼­ SeÀº ´ëÁ¶±ºº¸´Ù ³·¾ÒÀ¸³ª Åë°èÇÐÀû À¯ÀǼºÀº ¾ø¾ú°í (p>0.05),
ZnÀº ¾ç±º¿¡¼­ À¯»çÇÏ¿´´Ù.
4. ºÒÀÓ±ºÀÇ I±º, ¥±±º ¹× ¥²±º°£ ¹Ì·®±Ý¼ÓÄ¡´Â °¢ ±º°£¿¡ À¯ÀÇÇÑ Â÷ÀÌ´Â ¾ø¾ú´Ù (p>0.05).
5. Á¤ÀÚÀÇ ¿îµ¿¼º°ú È£¸£¸óÄ¡´Â Ç÷Àå ¹× Á¤Àå¾×³» Zn°ú SeÄ¡¿Í »ó°ü°ü°è´Â ¾ø¾ú´Ù.
ÀÌ»óÀ¸·Î Á¤Àå¾×³» Zn, Se¼ººÐÀº ´ëÁ¶±º°ú ºÒÀÓ±º»çÀÌ¿¡ À¯ÀÇÇÑ Â÷ÀÌ´Â ¾øÀ¸³ª, ¹Ì·®À¸·Î
Á¸ÀçÇÔ¿¡µµ ºÐ±¸ÇÏ°í ±× ³óµµº¯È­´Â °íȯÀÇ Á¶Á¤±â´É, Á¤ÀÚÀÇ »ýÁ¸ ¹× ±â´ÉÀ¯Áö¿¡ ½É°¢ÇÑ
Àå¾Ö¸¦ À¯¹ßÇÒ °ÍÀ¸·Î »ý°¢µÈ´Ù.
#ÃÊ·Ï#
Zinc (Zn) and Selenium (Se) were analysed in seminal and blood plasmas from 60
male infertility group and 10 normal control group. The concentrations of Zn and Se
were estimated by atomic absorbance spectrophotometry (AAS, Smith-hieftje-4000,
Thermo-Jarrel-Ash, USA). Seminal plasma Zn and Se in control group and infertility
group were 146.3 ¡¾ 41.5 §¶/§¢, 152.4¡¾61.4 §¶/§¢ and 0.074¡¾0.03 §¶/§¢, 0.068¡¾0.03 §¶/
§¢, respectively. Blood plasma Zn and Se in control group and infertility group were 1.65
¡¾0.62 §¶/§¢, 1.56¡¾0.54 §¶/§¢ and 0.084¡¾0.02 §¶/§¢, 0.082¡¾0.04 §¶/§¢, respectively. In
control group, the concentration of Zn in seminal plasma was significantly higher than
in blood plasma (p<0.01) and Se was higher in blood plasma than in seminal plasma
(p>0.05). In infertility group, the concentration of Zn in seminal plasma was significantly
higher than in blood plasma (p<0.05) and Se was significantly higher in blood plasma
than in seminal plasma (p<0.05). The Zn and Se in seminal and blood plasmas repealed
no statistically significant differences according to sperm density and plasma FSH, LH,
testosterone and prolactin level (p>0.5). As a result, we suggest that the .ole of Zn and
Se in male infertility may have directly effects on sperm function and spermatogenesis.

Å°¿öµå

Male infertility; Zinc; Selenium;

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