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Evaluation of the Changes of Coagulation-Fibrinolysis System during Transurethral Resection of the Prostate by Thromboelastography
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±èÅÂÇå/Tae Hun Kim
¾ç´ë¿/±è¼º¿ë/±èÇÏ¿µ/À¯È«¼º/ÃÖÇö/À±¿µÁØ/Dae Yul Yang/Sung Yong Kim/Hayoung Kim/Hong Seong Yoo/Hyun Choi/Young Joon Yoon
KMID : 0358319970380111217
Abstract
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We studied intraoperative changes of transurethral resection of the prostate in blood
coagulation-fibrinolysis system by thromboelastography (TEG) in 31 patients with
benign prostatic hpyerplasia. As TEG parameters reaction time (R), clot formation time
(K), maximum amplitude (MA), coagulation time (R+K), clot lysis index after 60
minutes (Ly60) were measured. The coagulability was evaluated by R and R+K, the
absolute strength of clot by MA, fibrinolysis by Ly60. Coagulation time (R+K) was
shortened in patients with decreased platelet count under 30,000 ¥ì/L (p<0.05), irrigating
fluid volume over 20,000 ml (p<0.05) and a tendency of shortening in patient with
resection time over 50minutes (p=0.078). MA had a tendency of increasing but
significant contributing factor was not detected. The mean value of Ly60 was increased
significantly but the change was in normal range. Irrigating fluid volume (r=0.407,
p<0.05) and resection time (r=-0.456, p<0.05) showed negative correlation significantly
the change of R+K. There was no significant correlation between resected prostatic
weight and TEG parameters. We concluded that coagulability is increased during TURP
suggesting a possible role in postoperative clot retention, but the risk of fibrinolysis is
not increased in with normal coagulation-fibrinolysis system.
Å°¿öµå
TURP; Thromboelastography; Coagulation-fibrinolysis system.;
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