간질성방광염에서 사구체화의 진단적 의의
The Significance of Glomerulation in the Diagnosis of Interstitial Cystitis
김장환, 마상열,
소속 상세정보
김장환 ( )
연세대학교 의과대학 피부과학교실
마상열 ( )
연세대학교 의과대학 비뇨기과학교실
KMID : 0358319970380121343
Abstract
결론
25명의 간질성방광염 환자와 12명의 대조군에서 마취 하에 방광팽창을 시행하고 사구체화
를 비교한 결과 두 군간의 발생 빈도는 통계학적으로 차이는 없었으나, 사구체화의 발생 정.
도가 간질성방광염 환자에서 심하였다. 이는 또한 방광의 질환에 관계없이 방광 팽창시 발
생하는 방광 점막의 손상에 의해 발생하는 것으로 생각된다.
간질성방광염에서 사구체화의 진단적 가치는 감수성 92.0%, 특이성 16.7%로, 사구체화는
간질정 방광염에서 비특이적 현상으로 여겨진다.
#초록#
An objective finding for the diagnosis of interstitial cystitis (If) is the so called
'glomerulation', petechial hemorrhages that occur after distention of the bladder,
Glomerulation occurs in most IC patients and although there are some reports that it
occurs in the normal bladder as well, there has been no actual study carried out to
confirm this and further study into this matter is needed. Therefore, we induced
glomerulations in non-IC patients and compared its frequency and severity with IC
patients in order to elucidate the importance of glomerulation in IC.
25 (10 males, 15 females ; mean age 44.3 years) If patients received hydrodistention
between Jan 1992 to Sep 1996 at the Department of Urology at Yongdong Severance
Hospital. 12 (8 males, 4 females; mean age 47.5 years) non-IC patients who were to
receive urological surgery under spinal or general anesthesia were selected for
hydrodistention; there were 6 ureter stone, 4 BPH, and 2 stress urinary incontinence
patients. 92.0% (23/25) of If patients and 83.3% (10/12) of non-IC patients showed
glomerulation and there was no statistical significance between the two groups. 76.0% (6
grade 2, 13 g.rode 3 glomerulation) of IC patients and 50.0% (3 grade 2, 3 Brade 3) of
non-IC patients showed glomerulation of grade 2 or higher. The frequency and severity
of glomerulation was in an inverse relationship with trabeculation of the bladder.
The sensitivity of glomerulation in the diagnosis of It was 92.0% whereas the
specificity was low with 16.7%. These findings suggest that glomerulation is nonspecific
in IC and warrants further investigation.
키워드
Interstitial cystitis; Glomerulation; Hydrodistention;
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