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ô¼öÀÌÇü¼º ȯ¾Æ¿¡¼­ ½Å°æ¿Ü°ú ¼ö¼úÀÇ ¿ä·ù¿ªÇÐÀû È¿°ú Urodynamic Evaluation of Neurosurgical Effect in Myelodysplasia

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Abstract

°á·Ð
¼Ò¾Æ ô¼öÀÌÇü¼º ȯ¾Æ¿¡¼­ ½Å°æ¿Ü°úÀû ¼ö¼úÀÇ È¿°ú¸¦ Æò°¡Çϱâ À§ÇØ ¼ö½½ ÀüÈÄ·Î ºñµ¥¿À
¿ä·ù¿ªÇа˻簡 ½ÃÇàµÈ 24·Ê¸¦ ºÐ¼®ÇÏ¿´´Ù. ¸ðµç ȯ¾ÆµéÀº ¼ö¼ú°úÁ¤ Áß Ã´¼ö À¯ÂøÁ¦°Å¼úÀ»
¹Þ¾ÒÀ¸¸ç, 20·Ê¿¡¼­´Â ¼úÈÄ 6°³¿ù¿¡¼­ 1³â »çÀÌ¿¡ ¿ä·ù¿ªÇа˻簡 ½ÃÇàµÇ¾ú°í, 4·Ê´Â ¼úÈÄ 3
°³¿ù¿¡ °Ë»ç°¡ ½ÃÇàµÇ¾ú´Ù.
¿ä·ù¿ªÇÐ°Ë»ç µµÁß ¹æ±¤±Ù ¼öÃàÀÌ ³ªÅ¸³­ ȯ¾Æ¿¡¼­´Â ºñ¾ïÁ¦¼º ¹æ±¤±Ù ¼öÃà À¯¹«°ú DSD
°¡ Á¶»çµÇ¾úÀ¸¸ç ¹«¹Ý»ç¹æ±¤ ȯ¾Æ¿¡¼­ ´Â ¿ä´©Ãâ¾Ð(leak pressure)ÀÌ ÃøÁ¤µÇ¾ú´Ù.
¼úÀü¿¡ Á¤»ó ¼Ò°ßÀ» ³ªÅ¸³»¾ú´ø ȯ¾ÆµéÀº 5·Ê¿¡¼­ ¼úÈÄ¿¡µµ Á¤»ó¼Ò°ßÀÌ À¯ÁöµÇ¾úÀ¸¸ç 1·Ê
¿¡¼­¸¸ÀÌ ¼úÈÄ¿¡ DSD¸¦ µ¿¹ÝÇÏÁö ¾ÊÀº ÆĹݻç¹æ±¤ ¾ç»óÀ» º¸¿´´Ù. ¼úÀü DSD¸¦ µ¿¹ÝÇÑ Á¤
»ó ¹æ±¤±Ù ¼öÃàÀº 1·Ê ÀÖ¾úÀ¸¸ç ¼úÈÄ¿¡ °í¾ÐÀÇ ¹«¹Ý»ç¹æ±¤À¸·Î º¯È­µÇ´Â ¾ç»óÀ» º¸¿´´Ù. 9
·Ê¿¡¼­ ¼úÀü¿¡ °ú¹Ý»ç¹æ±¤ÀÌ ³ªÅ¸³µÀ¸¸ç ±× Áß 4·Ê¿¡¼­´Â DSD°¡ µ¿¹ÝµÇ¾î ÀÖ¾ú´Ù. DSD°¡
µ¿¹ÝµÇÁö ¾ÊÀº 5·Ê Áß 4·Ê¿¡¼­ ¼úÈÄ ¿ä·ù¿ªÇÐ°Ë»ç ¼Ò°ßÀÇ º¯È­°¡ ÀÖ¾ú´Âµ¥, 1·Ê¿¡¼­´Â ¿ÏÀü
ÇÑ Á¤»ó¼öÃâ¹æ±¤À¸·Î ¹Ù²î¾úÀ¸¸ç 3·Ê¿¡¼­´Â Àú¾Ð ¹«¹Ý»ç¹æ±¤À¸·Î ³ªÅ¸³µ´Ù. DSD°¡ µ¿¹ÝµÈ
4·Ê¿¡¼­´Â 3·Ê¿¡¼­ ¼úÈÄ º¯È­°¡ ÀÖ¾úÀ¸¸ç, 2·Ê¿¡¼­ °í¾Ð ¹«¹Ý»ç¹æ±¤, 1·Ê¿¡¼­ ¹«±äÀå¹æ±¤
(atoruc bladder)À¸·Î º¯È­ÇÑ ¾ç»óÀ» º¸¿´´Ù. ¹«¹Ý»ç¹æ±¤Àº ¼úÀü¿¡ 7·Ê¿¡¼­ ¹ß°ßµÇ¾ú´Âµ¥, Àú
¾Ð ¹«¹Ý»ç¹æ±¤ 1·Ê, °í¾Ð ¹«¹Ý»ç¹æ±¤ 6·Ê¿´´Ù. Àú¾Ð ¹«¹Ý»ç¹æ±¤ 1·Ê´Â ¼úÈÄ¿¡ °í¾Ð ¹«¹Ý»ç¹æ
±¤À¸·Î º¯È­µÇ¾úÀ¸¸ç ¼úÀüÀÇ °í¾Ð ¹«¹Ý»ç¹æ±¤ 6·Ê Áß 3·Ê¿¡¼­ ¼úÈÄ º¯È­°¡ ³ªÅ¸³µÀ¸¸ç °¢°¢
DSD¸¦ µ¿¹ÝÇÑ °ú¹Ý»ç¹æ±¤ 2·Ê, ¹«±äÀå¹æ±¤ 1·ÊÀÇ ¼Ò°ßÀ» º¸¿´´Ù.
¿¬±¸ÀÚµéÀÇ Áõ·Ê ºÐ¼®¿¡ ÀÇÇÏ¸é ½Å°æ¿Ü°úÀû ¼ö¼ú ÈÄÀÇ ÁÖµÈ ¿ä·ù¿ªÇÐÀûÀÎ º¯È­´Â ¹æ±¤±Ù
È°µ¿ÀÇ °¨¼Ò·Î ³ªÅ¸³ª°í ÀÖ´Ù. ±×·¯³ª ¹æ±¤±Ù ¼öÃà¿¡ ´ëÇÑ ÀÌ·¯ÇÑ º¯È­°¡ ô¼öÀÌÇü¼º ȯ¾Æ
¿¡¼­ À¯ÀÍÇÑ È¿°ú¸¦ ³ªÅ¸³»Áö¸¸, ÀÌ·¯ÇÑ È¿°ú´Â ÀÜÁ¸ÇÏ´Â ¿äµµ°ý¾à±ÙÀÇ ±äÀåµµ¿¡ ÀÇÇØ ÀÓ»ó
ÀûÀ¸·Î Ä¿´Ù¶õ °³¼± È¿°ú¸¦ º¸Áö ¸øÇÏ´Â °ÍÀ¸·Î »ý°¢ÇÑ´Ù.
#ÃÊ·Ï#
Purpose: To evaluate neurosurgical effect in the pediatric patients with myelodysplasia
we reviewed preoperative and postoperative videourodynamic results.
Materials and Methods: All the 24 patients received untethering of spinal cord. Twenty
postoperative urodynamic studies were performed between 6 months and 1 year, and 4
were performed at 3 months after operation. Uninhibited contraction and
detrusor-sphincter dyssynergia(DSD) were checked in the patients having detrusor
contraction and leak pressure was measured in areflexic bladder.
Results: Preoperative normal urodynamic finding was found in 6 patients. Among them
one patient showed hyperreflexia with synergic voiding after operation. Normal detrusor
contraction with DSD was found in 2 patients preoperatively One of these patients
changed to high pressure areflexia Nine patients showed hyperreflexia preoperatively.
Four patients among them had DSD. Five hyperreflexic bladders without DSD showed
normoreflexia without 858 in one, low pressure areflexia in 3 and no change in one after
operation. Out of four patients with hyperreflexia having DSD 2 showed high pressure
areflexia, 1 showed atomic bladder and no change was seen in one. Seven patients had
areflexia preoperatively. One patient with low pressure areflexia preoperatively showed
high pressure areflexia postoperatively and 6 patients with high pressure areflexia
preoperatively showed hyperreflexia with DSD in two and atonic bladder in one and no
changes in 3 patients.
Conclusions: From the above data we think that main urodynamic effect by
neurosurgical treatment is decreasing detrusor activity. Although this effect on detrusor
contraction is likely to be beneficial to myelodysplastic patients, more durable sphincteric
activity may offset this profit.

Å°¿öµå

Myelodysplasia; Urodynamic study; Neurosurgical treatment;

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