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Abstract

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¼±¾ÏÀº 50¼¼ ÀÌ»óÀÇ ¹Ì±¹³²¼º¿¡¼­ °¡Àå ÈçÇÑ Á¾¾çÀ̸ç, ¹Ì±¹¿¡¼­ Á¾¾çÀ¸·Î ÀÎÇÑ »ç¸Á¿øÀÎ
Áß µÎ ¹ø°·Î ¸¹Àº ÁúȯÀÌ´Ù. ´ëºÎºÐÀÇ Àü¸³¼±¾ÏÀº ù Áø´Ü ½Ã Àü¸³¼± ¹ÛÀ¸·Î ÁøÇàµÈ »óÅÂ
À̸ç, ÀÌ·¯ÇÑ º´±âÀÇ Àü¸³¼±¾ÏÀº ¿¹ÈÄ°¡ ÁÁÁö ¾Ê°í, Ä¡·á ¶ÇÇÑ °í½ÄÀûÀÎ ¹æ¹ýÀ¸·Î Á¦ÇѵȴÙ.
µû¶ó¼­ ±Ù·¡ Àü¸³¼±¾Ï Á¶±âÁø´ÜÀÇ Á߿伺ÀÌ °­Á¶µÇ°í ÀÖ°í, ±× ¼±º°°Ë»ç ¹æ¹ý¿¡ ´ëÇÑ ¿¬±¸
°¡ °è¼ÓµÇ°í ÀÖ´Ù ÇöÀç Á÷Àå¼öÁö°Ë»ç, Ç÷û Àü¸³¼± ƯÀÌ Ç׿øÄ¡¿Í °æÁ÷Àå ÃÊÀ½Æİ˻簡 ³Î
¸® ÀÌ¿ëµÇ°í ÀÖÀ¸³ª, Àü¸²¼±¾ÏÀÇ Áø´Ü¿¡ ´ëÇÑ °¡Ä¡ ¹× »ýÁ¸À² °³¼± ¿©ºÎ´Â ¾ÆÁ÷ È®½ÇÈ÷ ÀÔ
ÁõµÇÁö ¾Ê¾Ò´Ù. ÀúÀÚµéÀº ¹è´¢Áõ»óÀ» ÁÖ¼Ò·Î ³»¿øÇÏ¿© Á÷Àå¼öÁö°Ë»ç, Ç÷û Àü¸³¼±Æ¯ÀÌÇ׿ø°Ë
»ç, °æÁ÷Àå ÃÊÀ½ÆÄ°Ë»ç ¹× Àü¸³¼±»ý°ËÀ» ½ÃÇàÇÑ È¯ÀÚµéÀ» ´ë»óÀ¸·Î ±× °á°ú¸¦ ºÐ¼®ÇÏ¿©, ¼¼
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#ÃÊ·Ï#
Purpose: We designed the study to compare the efficacy of digital rectal
examination(DRE), serum prostate specific antigen(PSA) & transrectal ultrasonography
(TRUS) for the early detection of prostate cancer.
Materials and Methods: We analyzed the result of the prostate biopsies of 162 patients
with abnormal hard nodule or asymmetricity on DRE, elevated serum PSA(>4ng/ml) or
hypoechoic lesion in peripheral zone on TRUS from August 1994 to June 1997.
Results: Of 162 patients, 26 patients(16%) had prostate cancer and 136 patients(84%)
were diagnosed as benign prostatic hyperplasia. DRE, serum PSA and TRUS had
sensitivities of 77%, 100% and 92%, respectively and positive predictive values(PPVs) of
48%, 26% and 19%, respectively. The sensitivities of high serum PSA(>4ng/ml) with
positive DRE, positive DRE with positive TRUS and high serum PSA with positive
TRUS were 77%, 73% and 92%, respectively and the PPVs were 65%, 51% and 34%,
respectively. In cases both DRE and TRUS were positive with high serum PSA,
sensitivity and PPV were 73% and 68%, respectively
Conclusions: The combination of DRE and serum PSA would be recommended as a
first line examination in the diagnosis of prostate cancer regarding the sensitivity and
PPV. (Korean J Urol 1998; 39: 4y2¡­5)

Å°¿öµå

Prostate cancer; Digital rectal examination; Prostate specific antigen; Transrectal ultrasonosraphy;

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