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¼Ò¾Æ ¹æ±¤¿ä°ü¿ª·ù¿¡¼­ ½Å¹ÝÈç °Ë»öÀ» À§ÇÑ 99mTc-DMSA SPECTÀÇ È¿¿ë¼º The Efficacy of 99mTc-DMSA SPECT in Diagnosis of Renal Scarringn of Vesicoureteral Reflux in Children

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Abstract

¼­·Ð
¼Ò¾Æ ¹æ±¤¿ä°ü¿ª·ù½Ã µ¿¹ÝµÇ´Â ¿ä·Î°è ÀÌ»ó°ú ½Å¹ÝÈç À¯¹«¸¦ °Ë»çÇÏ¿© Á¶±âÁø´Ü°ú Ä¡·á¸¦
ÇÔÀ¸·Î ÈÄ¿¡ ¹ß»ýÇÒ ¼ö ÀÖ´Â °íÇ÷¾Ð, ½ÅºÎÀü µîÀÇ ½Å¼Õ»óÀ» ¿¹¹æÇÏ´Â °ÍÀÌ ´ë´ÜÈ÷ Áß¿äÇÏ´Ù.
¹æ±¤¿ä°ü¿ª·ù(VUR)¿¡ ÀÇÇÑ ½Å¹ÝÈçÀÇ Áø´ÜÀº Á¾·¡ IVP»óÀÇ ½Å¹èÀÇ °ïºÀº¯Çü°ú ÀÌ¿¡ ¼ö¹ÝµÈ
½ÅÇÇÁúÀÇ À§ÃàÀ¸·Î ÆľÇÇÏ¿© ¿ÔÀ¸¸ç, USG¿¡¼­´Â ½ÅÇÇÁúÀÇ ÇÔ¸ô ¹× À§ÃàÀ¸·Î Áø´ÜÇÏ¿© ¿ÔÀ¸
³ª, ¿À´Ã³¯ INP´Â ½ÅÀ±°ûÀ» ÆľÇÇϴµ¥ ¾î·Á¿òÀÌ ÀÖÀ¸¸ç ÃÖ±Ù ¿µ»ó Áø´ÜÀÇ ¹æ¹ýÀÌ °³¼±µÊ¿¡
µû¶ó 99mTc-DMSA½ÅÁÖ»ç µîÀÇ ÀÌ¿ëÀ¸·Î ´õ¿í ¼±¸íÇÑ ½ÅÀ±°ûÀ» ¾ò°Ô µÇ¾ú
´Ù.
ÀÌ»ó°ú °°ÀÌ ½Å¹ÝÈç Áø´ÜÀÇ ÃÊ±â ´Ü°è °Ë»ç·Î¼­ IVP, ÃÊÀ½ÆÄ°Ë»çUSG),
99mTc-DMSA planar µîÀÌ ÀÖÀ¸³ª, ÃÖ±ÙÀÇ º¸°íµéÀº 3Â÷¿øÀû ÀÔü¿µ»óÀÇ
99mTC-DMSA SPECT°¡ ½Å°¨¿° Ãʱ⿡ °¨¿°ÀÇ À§Ä¡¿Í ½Å¹ÝÈçÀ» ¾Ë¾Æ³»´Âµ¥
´õ À¯¿ëÇÏ°í ¿¹¹ÎÇÑ °Ë»ç¹æ¹ýÀ̶ó°í ÇÑ´Ù ÀúÀÚµéÀº ¼Ò¾Æ ¹æ±¤¿ä°ü¿ª·ù½Ã »ó±â °Ë»çµé¿¡ ÀÇ
ÇÑ ½Å¹ÝÈç °Ë»çÀÇ À¯¿ëµµ¸¦ ºñ±³ ºÐ¼®ÇÏ¿´´Ù.
#ÃÊ·Ï#
Purpose : The diagnosis of renal scarring is very important for the pediatric patient
because it has been associated with the later development of hypertension, renal failure,
and end-stage kidney disease. Recent studies indicate that the sensitivity and specificity
of the99mTc-DMSA single photon emission computerized tomography
(SPECT) is better than IVP, USG, and 99mTC-DMSA Planar ThG
Purpose Of this Study iS tO Compare 2 types Of 9%nTh DMSA renal scan(planar and
SPECT) and IVP/USG in the diagnosis of renal scars.
Materials and Methods : We reviewed retrospectively the data of 49 children(72 renal
units) with vesicoureteral reflux(VUR) who underwent renal cortical imaging with
IVP/USG from January 1987 to August 1996. Patient ages ranged from 3 months to 14
years with a mean age 3.7 years. There were 17 boys and 12 girls(44 venal units) with
99mTc-DMSA planar with IVP/USG, and 12 boys and 8 girls(28 renal
units) with 99mTc-DMSA SPECT with IVP/USG.
Results : The 99mTc-DMSA planar imaging identified 94.7% sensitivities
while 99mTC-DMSA SPECT imaging identified 96.3% Sensitivities. And
the IVP/USG identified 75.3% sensitivities.
Conclusions : Recently, the 99mTc-DMSA renal scan has replaced
IVP/USG in detecting renal scarring. And we show that 99mTc-DMSA
SPECT studies are superior to IVP/USG, 99mTc-DMSA planar studies in
detecting renal scarring. We believe that the role of 99mTc-DMSA SPECT
will become increasingly important in detecting renal scarring of VUR.
(Korean J Urol 1998; 39: 627¡­32)

Å°¿öµå

Renal scar; Vesicoureteric reflux; 99mTc-DMSA planar 99mTc-DMSA SPECT;

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