우연히 발견된 신세포암의 임상분석: 최근 8년간의 경험
Clinical Analysis of Incidentally Found Renal Cell Carcinoma: Experiences of Recent 8 Years
소속 상세정보
이해원/Hae Won Lee
조규선/정현/윤상진/조문기/이은식/이상은/최황/이종욱/Kyu Seon Cho/Hyeon Jeong/Sang Jin Yoon/Moon Ki Jo/Eun Sik Lee/Sang Eun Lee/Hwang Choi/Chongwook Lee
KMID : 0358319980390100982
Abstract
결론
최근 증가하는 추세에 있는 우연히 발견된 신세포암은 증상이 동반된 신세포암과 비교하
여 보았을 때 우연암의 경우 병기 T2이하의 병기를 보인 경우가 81.5%를 차지하여 증상이
있던 환자에서의 64.3%보다 유의하게 저병기의 환자가 많았으며(p<005), 2년 및 5년 생존율
은 각각 78%와 67%로 증상이 있던 환자에서의 72%와 56%보다 유의하게 높은 점을 고려
할 때 양호한 임상경과를 보이는 것으로 파악되었다. 신세포암의 경우 진행된 경우에는 화
학요법이나 면역요법, 방사선요법 등에 잘 반응하지 않으므로 전체 환자들의 생존율을 높이
기 위해서는 우연히 발견된 신세포암과 같이 낮은 병기의 종양을 찾는 노력이 경주되어야
할 것으로 판단된다.
#초록#
Purpose : The clinical information and survival rate of incidentally found renal cell
carcinoma patients were compared with those of symptomatic patients.
Materials and Methods : We reviewed the hospital records of 267 patients with renal
cell carcinoma managed in Seoul National University Hospital during the recent 8 years.
Mean followup period was 26±21.1 months. Initial presentations, pathologic stages, and
survivals were analysed.
Results : In 124 patients(46.4%), the tumors were found incidentally. Hematuria, pain
and mass were the common presentations in symptomatic patients. The more patients
with lower stage(stage T1 and T2) belonged to incidentally found group compared with
symptomatic group(81.5% vs 64.3%). The 2 and 5-year survival rates of incidentally
found group were 78% and 67%, respectively, which were higher than those of
symptomatic group(72% and 56%). The survival rate decreased markedly by increasing
size, advanced stage, lymph node involvement and distant metastasis.
Conclusions : Recently, there has been a significant increase of incidentally detected
renal cell carcinoma and the incidentally found renal cell carcinoma proved to have
better prognosis than symptomatic group. So our effort should be focused on detecting
low stage incidentallomas.
키워드
Renal cell carcinoma; Asymptomatic; Incidentalloma;
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