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Abstract

°á·Ð
1985³âºÎÅÍ 1995³â±îÁö °í½Å´ëÇб³ º¹À½º´¿ø ºñ´¢±â°ú¿¡¼­ »óºÎ¿ä·Î ÀÌÇà»óÇǼ¼Æ÷¾ÏÀ¸·Î
Áø´Ü¹ÞÀº 32·Ê¸¦ ´ë»óÀ¸·Î »ýÁ¸À²¿¡ ´ëÇÑ ÈÄÇâÀû Á¶»ç¸¦ ÇÏ¿© ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù
Àüü ȯÀÚÀÇ 2³â ¹× 5³â »ýÁ¸À²Àº °¢°¢ 45%¿Í 32%¿´´Ù. »ýÁ¸À²¿¡ ¿µÇâÀ» ÁÖ´Â ¿¹ÈÄÀÎÀÚÀÇ
ºÐ¼®¿¡¼­ stage T1°ú T2´Â 5³â »ýÁ¸À²ÀÌ 100%¿Í T1%¿´À¸³ª T3¿Í T4¿¡¼­ ´Â 5³â±îÁö »ý
Á¸ÀÚ°¡ ¾ø¾úÀ¸¸ç grade ¥°°ú ¥±´Â 5³â »ýÁ¸À²ÀÌ 100%¿Í 56%¿´À¸³ª grade ¥²¿Í ¥³¿¡¼­´Â 5
³â±îÁö »ýÁ¸ÀÚ°¡ ¾ø¾ú´Ù. µû¶ó¼­ »óºÎ¿ä·Î ÀÌÇà»óÇǼ¼Æ÷¾ÏÀÇ ¿¹ÈÄ¿¡ °¡Àå ¿µÇâÀ» ¹ÌÄ¡´Â ¿¹
ÈÄÀÎÀÚ´Â º´±â¿Í º´¸®Á¶Á÷ÇÐÀû ¼¼Æ÷ºÐÈ­µµ¶ó°í »ý°¢µÇ¸ç low stage low grade ȯÀÚµéÀº Á¶
±â ¼ö¼ú·Î ³ôÀº »ýÁ¸À²ÀÌ ±â´ëµÇÁö¸¸ high stage high grade ȯÀÚµéÀÇ °æ¿ì »ýÁ¸À²ÀÇ °³¼±
À» À§ÇØ ¼ö¼úÀûÀÎ ¹æ¹ý¿Ü¿¡µµ º¸´Ù È¿°úÀûÀÎ ºÎ°¡Àû Ä¡·á¹æ¹ýÀÌ ÇÊ¿äÇϸ®¶ó »ý°¢µÈ´Ù
#ÃÊ·Ï#
Purpose : Transitional cell carcinoma involving upper urinary tract is relatively
uncommon. We analyzed 5-year survival rate and prognostic factors in transitional cell
carcinoma of the upper urinary tract.
Materials and Methods : Survival and prognostic factors were assessed with
histopathological examination in 32 patients operated between 1985 and 1995. Patient age
ranged from 34 to 87 years, with an average of 63.3 years. Prognostic factors such as
stage, grade, age, location of tumor, patient's status, urine cytology, and synchronous
and metachronous bladder tumor were investigated.
Results : The 2-year and 5-year survival rates were 45% and 32%, respectively. The
most significant prognostic factors were stage and grade. Pathologically, 18.7% of the
patients were stage T1, 21.9% stage T2, 28.1% stage T3 and 31.3% stage T4, and 5
years survival rates of 32 patients were l00%, 71%, 0% and 0% for stage Tl, T2, T3
and T4 disease, respectively. Histologically, 9.4% of patients had grade ¥°, 40.6% grade
¥±, 25.0% grade ¥² and 25.0% grade ¥³ disease, and 5-year survival rates of patients
were 100%, 56%, 0% and 0% for grade ¥° to ¥³ disease, respectively.
Conclusions : This finding suggests that early diagnosis and surgical excision of the
upper urinary tract tumor will result in excellent outcome but prognosis of high stage
and high grade tumor was poor. Therefore, high stage and high grade tumor is required
effective adjuvant therapy for improvement of survival.

Å°¿öµå

Upper urinary tract; Transitional cell carcinoma; Prognostic factors;

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