Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

¼¼ °¡ÁöÀÇ ¼­·Î ´Ù¸¥ µ¿¼Ò¼º ¹æ±¤´ëÄ¡¼ú ÈÄ »óºÎ¿ä·Î º¯È­¿Í ´ë»ç¼º»êÁõÀÇ ¹ß»ý Change of the Upper Urinary Tracts and Occurrence of Metabolic Acidosis after Three Different Orthotopic Bladder Substitutions

´ëÇѺñ´¢±â°úÇÐȸÁö 1998³â 39±Ç 12È£ p.1254 ~ 1258
ÀÌÁøÇü, ±èû¼ö, ¾ÈÇÑÁ¾,
¼Ò¼Ó »ó¼¼Á¤º¸
ÀÌÁøÇü (  ) 
¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ºñ´¢±â°úÇÐ

±èû¼ö (  ) 
¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ºñ´¢±â°úÇÐ
¾ÈÇÑÁ¾ (  ) 
¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ºñ´¢±â°úÇÐ

Abstract

¼­·Ð
ħÀ±¼º ¹æ±¤¾ÏÀ¸·Î ±ÙÄ¡Àû ¹æ±¤ÀûÃâ¼ú ÈÄÀÇ ¿ä·Î Àç°Ç¿¡´Â 1950³â´ë¿¡ Couyelaue¿¡ ÀÇÇØ
ileal neobladder°¡ µµÀÔµÈ ÀÌ·¡ ÇöÀç´Â ´Ù¾çÇÑ ¼ú½ÄÀÇ ¹æ±¤´ëÄ¡¼úÀÌ ÀÌ¿ëµÇ°í ÀÖ´Ù.
µ¿¼Ò¼º ¹æ±¤´ëÄ¡¼ú(orthotoplc bladder substitution)Àº ¿Ü¿äµµ±¸¸¦ ÅëÇÑ ¹è´¢¸¦ °¡´ÉÇÏ°Ô ÇÔ
À¸·Î½á ±âÁ¸ÀÇ È¸Àå µµ°ü Á¶¼º¼ú°ú ½Ç±ÝÇü ¶Ç´Â ºñ½Ç±ÝÇü ¿ä·ÎÀüȯ¼úº¸´Ù ȯÀÚµéÀÇ »îÀÇ Áú
À» Çâ»ó½Ãų ¼ö ÀÖ¾ú´Ù µ¿¼Ò¼º ¹æ±¤´ëÄ¡¼úÀÇ ¸ñÇ¥´Â »óºÎ¿ä·Î º¸Á¸°ú ÇÔ²² ¿ä½Ç±ÝÀÌ ¾ø¾î¾ß
ÇÏ¸ç µ¿½Ã¿¡ ÀûÀýÇÑ ½Ã°£ °£°ÝÀ¸·Î ¿äµµ¸¦ ÅëÇÑ ¹è´¢¸¦ °¡´ÉÇÏ°Ô ÇÏ´Â °ÍÀÌ´Ù ¶ÇÇÑ ÀåÀ¸·Î
´ëÄ¡µÇ´Â ¹æ±¤Á¶¼º¿¡ µû¸¥ ¿©·¯ °¡Áö ´ë»çÀå¾Ö°¡ Àû¾î¾ß ÇÑ´Ù
»óºÎ¿ä·Î¸¦ º¸Á¸Çϱâ À§Çؼ­´Â ÃæºÐÇÑ ¹æ±¤¿ëÀû, ³·Àº ¹æ±¤³»¾Ð, ³ôÀº ź·Â¼º°ú ÇÔ²² ÀûÀý
ÇÑ ¿äÀÇ ¹èÃâ·Î ÀÜ´¢°¡ Àû¾î¾ß ÇÏ¸ç ½ÅÀåÀ¸·ÎÀÇ ¿ª·ù°¡ ¾ø¾î¾ß ÇÑ´Ù. ÃæºÐÇÑ ¿ëÀû°ú ³·Àº
¹æ±¤³»¾ÐÀ» À¯ÁöÇϱâ À§ÇØ Àå°£¸·´ëÃø¿¡¼­ ȸÀåÀ» Àý°³(detubularlzatlon)ÇÏ´Â ¹æ¹ýÀÌ 1959³â
Goodunna¿¡ ÀÇÇØ Ã³À½ ½ÃÀ۵Ǿú´Âµ¥, ÀÌ´Â ¹æÇ⼺ÀÖ´Â ¿¬µ¿¿îµ¿À» ¼Ò½Ç½ÃÄѼ­ ÀåÀ¸·Î ´ëÄ¡
µÈ ¹æ±¤ÀÌ Àú¾Ð°ú ³ôÀº ź·Â¼º ±×¸®°í Å« ¿ëÀûÀ» °¡Áú ¼ö ÀÖ°Ô ÇÏ¿´´Ù. ÇÑÆí ÀÌ½ÄµÈ ¿ä°üÀÇ
Æó»ö¾øÀÌ ½ÅÀåÀ¸·ÎÀÇ ¿ª·ù¸¦ ¹æÁöÇϱâ À§ÇÑ ¿©·¯ °¡Áö ¹æ¹ýµéÀÌ °³¹ßµÇ¾î ÇöÀç »ç¿ëµÇ°í ÀÖ
´Âµ¥ ÀúÀÚµéÀº Á¡¸·ÇÏÅͳιæ¹ý ±ÙÀ§È¸ÀåÀýÀ» ÀÌ¿ëÇÑ Á÷Á¢¹®ÇÕ¹æ¹ý, serous-hn8d º®¿ÜÅͳιæ
¹ýÀ» Àû¿ëÇÏ¿© °¢°¢ÀÇ Ç׿ª·ù¹ý¿¡ µû¸¥ ¼ö¼ú ÀüÈÄ »óºÎ¿ä·ÎÀÇ º¯È­¸¦ ºñ±³ÇÏ¿´´Ù
¹æ±¤Á¶¼º ÈÄ ¿©·¯ °¡Áö ´ë»çÀå¾Ö Áß ´ë»ç¼º»êÁõÀº Áß¿äÇÑ ¹®Á¦Á¡ ÁßÀÇ Çϳª·Î ¾Ë·ÁÁ® ÀÖ´Ù
±×¸®°í ±ÙÀÚ¿¡ ¿ä·ÎÀç°Ç¼ú¿¡ ÀÌ¿ëµÈ ÀåÀÇ ±æÀÌ¿Í ¼ö¼ú ÈÄ¿¡ ¹ß»ýÇÏ´Â ´ë»ç¼º »êÁõÀÇ ¹ß»ý»ç
ÀÌ¿¡ »óÆÇ °ü°è°¡ ÀÖ´Â °ÍÀ¸·Î ¹àÇôÁ³´Ù. ÀúÀÚµéÀº ¿ä·ÎÀç°Ç¿¡ ÀÖ¾î ¼­·Î ´Ù¸¥ ±æÀÌÀÇ ÀåÀ»
ÀÌ¿ëÇÏ¿´´ø À§ÀÇ ¼¼°¡Áö ¼ú½ÄÀ» ÅëÇØ ¼ö¼ú ÈÄ ¹ß»ýÇÑ ´ë»ç¼º»êÁõ°ú ÀÌ¿ëµÈ ÀåÀÇ ±æÀÌ¿ÍÀÇ
»ó°ü°ü°è¸¦ ¾Ë¾Æº¸¾Ò´Ù
#ÃÊ·Ï#
Purpose : Orthotopic neobladder following radical cystectomy are currently preferred to
the other urinary diversions. We have compared three different ureteroenteric
anastomoses regarding change of the upper urinary tracts and evaluated correlation
between the length of bowel used for bladder reconstruction and metabolic acidosis.
Materials and Methods : Between Sep. 92 and Jul. 97, 37 patient(range 34-69 yrs) with
bladder cancer underwent an orthotopic Mainz pouch with antireflux submucosal
tunnel(n=10), an ileal low-pressure bladder substitute with direct ureteroileal
anastomosis(Stuffier, n=15) and an ileal W-neobladder with serouslined ertramural
tunnel(Ghoneim, n=12) following radical cystectomy Mean follow up was 22 months(7-64
twos). IVP and VCUG were performed at 6, 12 months postoperatively and annually
thereafter. The measurement of serum electrolyte and/or arterial blood gas analysis were
carried out every 3-6 months.
Results : The vesicoureteral reflux occurred in 37%(11/30 renal unit) with Stuffier
pouch, 10%(2/20) with Mainz pouch, and none with Ghoneim(p=0.01). Moderate to severe
hydronephrosis resulting from reflux was noted in 4 renal units with Stuffier pouch,
while an atrophic kidney due to obstruction at ureteroenteric anastomosis was noted
with each Mainz pouch and Ghoneim. Metabolic acidosis was identified in 5
patients(33%) with an Stuffier pouch whereas it was noted in less than 10% with Mainz
pouch and Ghoneim(p=0.07). Two patients with deteriorated renal function need
bicarbonate replacement therapy for correction of metabolic acidosis.
Conclusions : Although most patients with direct ureteroileal anastomosis preserved
renal function, antireflux ureteroenteric anastomosis using submucosal tunnel or
serous-lined extramural tunnel is better in terms of occurrence of hydronephrosis and
vesicoureteral reflux. The length of bowel less than 45cm used for bladder
reconstruction may avoid metabolic acidosis

Å°¿öµå

Bladder substitution; Bladder neoplasms; Metabolic acidosis;

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

   

µîÀçÀú³Î Á¤º¸

KCI
KoreaMed
KAMS