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¹æ±¤¾Ï¿¡ À־ ¹æ±¤ÀûÃâ¼úÈÄ ¿äµµºÎ Á¾¾çÀÇ Àç¹ß Urethral Recurrence of Bladder Tumor after Total Cystectomy

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ÀÓ¼ººó (  ) 
Chungbuk National University

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Ãæ³²´ëÇб³ ÀÇ°ú´ëÇÐ ºñ´¢±â°ú

Abstract

¼­·Ð
½Å¹è¿¡¼­ ¿äµµ±îÁö À̾îÁö´Â Á¡¸·Àº ¿ä»óÇÇ·Î ±¸¼ºµÇ¾î ÀÖ°í, Ç׽à ¿ä¿¡ Á¢ÃËÇÏ°í ÀÖ´Ù´Â
°øÅëÁ¡À» °¡Áö°í ÀÖÀ¸¸ç, ¿©±â¿¡¼­ ¹ß»ýÇÏ´Â Á¾¾çµµ ´ëºÎºÐ ¿ä»óÇÇÁ¾¾çÀ¸·Î ÀÓ»óƯ¼º°ú ¾Ï
Çü¼º°úÁ¤ÀÌ µ¿ÀÏÇÏ´Ù. ¿ä»óÇÇ´Â ÀÌÇà»óÇǼ¼Æ÷·Î ±¸¼ºµÇ¾î À־ Á¾¾ç ¹ß»ý½Ã ÀÌÇà»óÇǼ¼Æ÷
Á¾¾çÀ̶ó°í ºÎ¸¥´Ù. ¹ß»ýºóµµ´Â ºÎÀ§¿¡ µû¶ó ´Ù¸£°í, ±×Áß ¹æ±¤Á¾¾çÀº ¿ì¸® ³ª¶ó ºñ´¢±â°è¾Ï
Áß °¡Àå ¸¹ÀÌ ¹ß»ýÇÑ´Ù. ÇÑÆí Á¡¸·ÀÌ µ¿ÀÏÇÑ »óÇÇ·Î ±¸¼ºµÇ¾î ÀÖ¾î »óºÎ¿ä·Î¿¡ Á¾¾çÀÌ ¹ß»ý
ÇÒ °æ¿ì ÇϺοä·Î¿¡¼­µµ µ¿ÀÏÇÑ ¼º°ÝÀÇ Á¾¾çÀÌ ¹ß»ýÇÒ ¼ö ÀÖ´Ù. µû¶ó¼­ ¹æ±¤ÀüÀûÃâ¼ú ÈÄ ¿ä
µµ¿¡¼­ ÀÌÇà»óÇǼ¼Æ÷¾ÏÀÌ Àç¹ßÇÒ ¼ö Àֱ⠶§¹®¿¡ ¿¹¹æÀû ¿äµµÀûÃâ¼úÀÇ Çʿ伺À» °­Á¶ÇÏ°Ô
µÇ¾ú´Ù. ÇÏÁö¸¸ ÀÌ·¯ÇÑ ¼±ÅÃÀº ¸ðµç ȯÀÚ¿¡¼­ Àû¿ëµÉ ¼ö ¾ø°í ´Ù¾çÇÑ À§ÇèÀÎÀÚÀÇ À¯¹«¿¡ µû
¶ó ¼±ÅÃÀûÀ¸·Î ½ÃÇàµÇ¾ß ÇÑ´Ù´Â ÁÖÀåÀÌ ÀÖ¾ú´Ù. ¶ÇÇÑ ÃÖ±Ù¿¡´Â ¹æ±¤ÀûÃâ¼úÈÄ¿¡ neobladder
¿Í °°Àº ¼ö¼ú¹æ¹ýÀÌ °í¾ÈµÇ¾î ÇϺοä·ÎÀÇ ¿¬¼Ó¼ºÀÌ ÇÊ¿äÇÏ°Ô µÇ¸é¼­ ¼±ÅÃÀûÀÎ ¿äµµÀûÃâ¼úÀÇ
ºñÁßÀÌ ³ô¾ÆÁö°Ô µÇ¾ú´Ù. ±×·¯³ª ´Ü¼øÇÑ ¿ä·ÎÀüȯ¼úÀÇ °æ¿ì¿¡´Â ¿äµµ¿¡¼­ ÀÌÇà»óÇǼ¼Æ÷¾ÏÀÌ
Àç¹ßµÉ °æ¿ì ¿äµµÀûÃâ¼úÀº °£´ÜÇÑ ¼ú±â·Î ó¸®ÇÒ ¼ö ÀÖÁö¸¸ ÀÌ¹Ì neobladder °°Àº ¼ö¼úÀ»
¹ÞÀº ȯÀÚ¿¡¼­ ¿äµµ¿¡ ÀÌÇà»óÇǼ¼Æ÷¾ÏÀÌ Àç¹ßµÉ °æ¿ì¿¡´Â º¹ÀâÇÑ ¼ú±â°¡ ÇÊ¿äÇÏ°Ô µÈ´Ù. µû
¶ó¼­ neobladder¸¦ ¸¸µé °æ¿ì´Â Àç¹ß À§Ç輺ÀÌ Àִ ȯÀÚ¿¡¼­´Â ¿äµµ¿Í reserviorÀÇ ¹®ÇÕÀ»
ÇÇÇØ¾ß ÇÑ´Ù´Â °á·ÐÀÌ ³ª¿À°Ô µÈ´Ù. ±×·¯³ª ¼ö¼úÀü ȤÀº ¼ö¼úÁß ÀÌ·¯ÇÑ ÆÇ´ÜÀ» ¿ëÀÌÇÏ°Ô ÇØ
ÁÙ ¼ö ÀÖ´Â ¸¸Á·ÇÒ ¸¸ÇÑ Áöħ¿¡ ´ëÇÑ º¸°í°¡ Àû´Ù. ÀÌ¿¡ ÀúÀÚ´Â ¹æ±¤¾ÏȯÀÚ¿¡¼­ ¹æ±¤ÀüÀûÃâ
¼úÀ» ½ÃÇàÈÄ ¿äµµ¿¡ ¾ÏÀÌ ¹ß»ýÇÏ´Â ºóµµ¸¦ ¾Ë¾Æº¸°í ÀÌ°ÍÀÌ Á¾¾çÀÇ º´±â, ºÐÈ­µµ, ¼ö ÇüÅÂ
¹× À§Ä¡ µî°ú ¹ÐÁ¢ÇÑ °ü°è°¡ ÀÖ´ÂÁö ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù.

Purpose: Multifocal development of transitional cell carcinoma in the urinary tract is
well recognized. We reviewed the urethral recurrence following cystectomy for
transitional cell carcinoma of the bladder and determined the factors influencing this
recurrence.
Materials and Methods: From January 1984 to December 1996, 97 patients underwent
total cystectomy in our hospital and 59 men were able to be followed up for transitional
cell carcinoma of the bladder. The incidence of the urethral recurrence after cystectomy
and its relationship to some factors including tumor stage, grade, number, shape, and
location of the bladder cancer were evaluated.
Results: Of the 59 patients, nine(15.3%) had secondary urethral cancer which was
more common in high stage & grade, multiple, sessile tumors and that involved the
trigone, bladder neck or prostate.
Conclusions: A proper evaluation of patients at high risk for subsequent development
of cancer in the urethra after cystectomy appears to be important to determine whether
or not preserve the urethra and to avoid unnecessary urethrectomy during the total
cystectomy.

Å°¿öµå

Bladder cancer; Urethral recurrence; Total cystectomy;

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