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Àü¸³¼±ºñ´ëÁõ ¼ö¼úÀû Ä¡·á°á°úÀÇ ¿ä¿ªµ¿ÇÐÀû ¿¹ÃøÀÎÀÚ Urodynamic Predictive Factors for Surgical Treatment Outcome of Benign Prostatic Hyperplasia

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Abstract

°á·Ð
Àü¸³¼±ºñ´ëÁõ ȯÀÚÀÇ Àü¸³¼±ÀýÁ¦¼ú ÈÄÀÇ °á°ú¸¦ ¿¹ÃøÇÒ ¼ö ÀÖ´Â ¿ä¿ªµ¿ÇÐÀû ÀÎÀÚ Áß¿¡¼­
4°¡ÁöÀÇ À¯¸®ÇÑ ÀÎÀÚ¿Í 8°¡ÁöÀÇ ºÒ¸®ÇÑ ÀÎÀÚ¸¦ ãÀ» ¼ö ÀÖ¾ú´Ù. 90% ÀÌ»óÀÇ ¼º°øÀ²À» º¸ÀÎ
À¯¸®ÇÑ ¿ä¿ªµ¿ÇÐÀû ¿¹ÃøÀÎÀÚ´Â ÃÖ´ë¿ä·ù¼Óµµ°¡ 10§¢/sec ¹Ì¸¸ compressive flow pattern, Àü
¸³¼±¿äµµÀÇ ±æÀÌ°¡ 6§¯ÀÌ»ó, Àü¸³¼±¿äµµ³» ÷»ó ¾Ð·Â»ó½ÂÀÌ ÀÖ´Â °æ¿ì¿´°í, 70% ÀÌÇÏÀÇ ¼º
°ø·üÀ» º¸ÀÎ ºÒ¸®ÇÑ ¿ä¿ªµ¿ÇÐÀû ¿¹ÃøÀÎÀÚ´Â intermittent or normal sow pattern, Àü¸³¼±¿ä
µµÀÇ ±æÀÌ°¡ 4§¯ ¹Ì¸¸, ÃÖ´ë¿äµµ¾Ð·ÂÀÌ 100§¯H2O ÀÌ»ó, Àü¸³¼±¿äµµ¿µ¿ªÀÌ70
§¯¡¤§¯H2O ¹Ì¸¸, ÃÖ´ë¹æ±¤¿ëÀûÀÌ 250§¢¹Ì¸¸, ÃÖ´ë¹æ±¤³»¾Ð<10§¯
H2O, Abrams-Griffiths nomogramÀÇ ºÐ·ù»ó ºñÆó»ö, ÃÖ´ë¿ä¼Ó½Ã ¹æ±¤³»¾ÐÀÌ
50§¯H2O ¹Ì¸¸ÀÎ °æ¿ì¿´´Ù. ÀÌ·¯ÇÑ ¿ä¿ªµ¿ÇÐÀû ¿¹ÃøÀÎÀÚµéÀ» °¢°¢ÀÇ È¯Àڵ鿡
°Ô Àû¿ë½ÃÄ×À» ¶§ ºÒ¸®ÇÑ ÀÎÀÚ ¾øÀÌ À¯¸®ÇÑ ÀÎÀÚ¸¦ 2°³ ÀÌ»ó °¡Áø ȯÀÚµéÀÇ ¼º°øÀ²Àº 93%
·Î ³ôÀº ¹Ý¸é ºÒ¸®ÇÑ ÀÎÀÚ¸¦ 1°³ ÀÌ»ó °¡Áø ȯÀÚµéÀÇ ¼º°ø·üÀº 61%, ºÒ¸®ÇÑ ÀÎÀÚ¸¦ 2°³ ÀÌ
»ó °¡Áø ȯÀÚµéÀÇ ¼º°ø·üÀº 48%·Î ³·°Ô ³ªÅ¸³µ´Ù. µû¶ó¼­ ºÒ¸®ÇÑ ÀÎÀÚ ¾øÀÌ À¯¸®ÇÑ ÀÎÀÚ°¡
2°³ ÀÌ»óÀÎ Àü¸³¼±ºñ´ëÁõ ȯÀÚ¿¡¼­´Â Àü¸³¼±ÀýÁ¦¼úÀ» ½ÃÇàÇÏ´Â °ÍÀÌ ¹Ù¶÷Á÷ÇÏ°ÚÀ¸³ª ºÒ¸®ÇÑ
ÀÎÀÚ°¡ 1°³ ÀÌ»óÀΠȯÀÚ¿¡¼­´Â Àü¸³¼±ÀýÁ¦¼úÀº ½ÅÁßÇÏ°Ô ¼±ÅõǾî¾ß ÇÒ Ä¡·á¹æ¹ýÀÌ´Ù.

Purpose : Transurethral prostatectomy(TURP) or open prostatectomy were considered
as standard treatments for benign prostatic hyperplasia(BPH), but these treatments
showed high morbidity and mortality. We searched urodynamic predictive factors for
successful surgical outcome to select patients who would benefit from prostatectomy
pre-operatively.
Material and Methods : Retrospectively, we reviewed preoperative urodynamic findings
of 114 patients with BPH undergoing TURP(104cases) or open prostatectomy(10cases).
Results : In the follow-up period of 1 month to 19 months, a strict successes were
achieved in 83 patients(73%). On analysis of the success rate, 4 favorable urodynamic
factors and 8 unfavorable urodynamic factors were noted. 4 favorable factors were as
follows ; maximal flow rate<10§¢/sec, compressive flow pattern, prostatic urethral
length>6§¯ and presence of peak elevation on prostatic urethra pressure. 8 unfavorable
factors were as follow ; intermittent or normal flow pattern, prostatic urethral length<4
§¯, maximal detrusor pressure<10§¯H2O, maximal bladder capacity<250§¢,
maximal urethral pressure>100§¯H2O, prostatic pressure area<70§¯¡¤§¯
H2O, non-obstructive pattern on Abrams-Griffiths nomogram and detrusor
pressure at maximal flow rate<50§¯H2O.
Conclusions : Patients with more than 1 unfavorable urodynamic factor should be
investigated carefully before surgery and be treated with other non-invasive treatment
for BPH. The presence of 2 favorable urodynamic factors without unfavorable factor will
usually predict the best surgical outcome.

Å°¿öµå

Benign prostatic hyperplasia; Urodynamic study; Predictive factor;

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