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ÇϺοä·ÎÁõ»óÀ» º¸ÀÌ´Â ³²¼º¿¡¼­ Àü¸³¼± Áõ»óÁ¡¼ö, Àü¸³¼±¿ëÀû, ¿ä¼Ó°Ë»ç °á°úÀÇ »ó°ü°ü°è Relationship among Symptom Score, Urinary Flow Rates, and Prostate Volume in 620 Men with Lower Urinary Tract Symptoms

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±è´ë¿µ/Dae Young Kim ¿À½ÂÁØ/ÀÌ°æö/°­Á¤À±/½ÉºÀ¼®/±Ç¼º¿ø/ÀÌ»óÀº/Seung June Oh/Kyeong Cheol Lee/Jeong Yoon Kang/Bong Suk Shim/Sung Won Kwon/Sang Eun Lee

Abstract

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Purpose: We aimed to investigate the relationships among age, International Prostate
Symptom Score(IPSS), uroflowmetry and prostate volume in men with lower urinary
tract symptom(LUTS).
Materials and Methods: Among the 847 men who participated in the BPH awareness
program, 620 men(73.2%) who had not LUTS or had LUTS without concomitant
conditions(except BPH) known to interfere with normal voiding wore selected. All of
them completed IPSS questionnaire, uroflowmetry and transrectal ultrasonography. We
calculated correlation coefficient to investigate the association among age, maximal flow
rate, mean flow rate, and prostate volume. Additionally, total men were stratified by 3
age groups and 3 IPSS groups, and we also evaluated relationships among the
parameters according to these groups.
Results: The statistically significant correlations were found among the age,
uroflowmetry and prostate volume. Total symptom score did not show significant
correlation with age. However, irritative symptom score increased with increasing age in
statistically significant manner. When we stratified men into three age groups, most of
the correlations were stronger in the younger than 60 years old group than those
observed in the entire population. According to a multivariate regression analysis, age
and prostate volume did not show statistically significant correlation with IPSS. When
the all men were classified according to the IPSS, there were significant differences
between maximal flow rate , mean flow rate and prostate volume.
Conclusions: Emerging from this analysis showed that age is the important factor
influencing the relationship among symptom score, urinary flow rate and prostate
volume. LUTS may be affected by some factor such detrusor tone as well as prostate
volume. We suggest that the development of more objective and sophisticated studies
such as urodynamic study, molecular biologic study for functional morphology of
detrusor and community-based study with longitudinal measurements will be necessary
to approach the pathogenesis of LUTS.

Å°¿öµå

Lower urinary tract symptom; International prostate symptom score; Age; Prostate volume;

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