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ÀÌÁö¿­/Ji Youl Lee À̽ÂÁÖ/Á¶¿µ·¡/±è¼¼¿õ/Á¶¿ëÇö/À±¹®¼ö/Seung Ju Lee/Young Lae Cho/Sae Woong Kim/Yong Hyun Cho/Moon Soo Yoon

Abstract

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ħÀ±¼º ¹æ±¤¾Ï ȯÀÚÀÇ Ä¡·á·Î ±ÙÄ¡Àû ¹æ±¤ÀûÃâ¼ú ¹× °ñ¹ÝÀÓÆÄÀý ÀýÁ¦¼úÀ» ½ÃÇàÇÑ µÚ ¿©·¯
°¡Áö ¹æ¹ýÀÇ ¿ä·ÎÀüȯ¼úÀÌ ½ÃÇàµÇ¾î ¿Ô´Ù. ±× Áß ¹æ±¤´ëÄ¡¼úÀº 1979³â Camey¿Í LeDucÀÌ
Camey procedure¸¦ ¹ßÇ¥ÇÑ ÀÌ·¡·Î ¿©·¯ ºÎÀ§ÀÇ ÀåÀ» ÀÌ¿ëÇÑ ´Ù¾çÇÑ ¹æ¹ýµéÀÇ ¹æ±¤´ëÄ¡¼ú
ÀÌ ¼Ò°³µÇ¾î ¿Ô´Ù. ÇöÀç±îÁö ¾Ë·ÁÁø intestinal neobladder°¡ °¡Á®¾ßÇÒ ÀÌ»óÀûÀÎ Á¶°ÇÀº 1)
ÃæºÐÇÑ ¹æ±¤¿ëÀû, 2) Ã游½Ã ³·Àº ¹æ±¤³»¾Ð, 3) ºÒ¾ÈÁ¤ÇÑ ¹æ±¤¼öÃàÀÌ ¾ø´Â ¾ÈÁ¤µÈ ¹æ±¤, 4)
¹è´¢ ÈÄ ÃÖ¼ÒÇÑÀÇ ÀÜ´¢, 5) ½ÅÀ¸·ÎÀÇ ¿ä¿ª·ù°¡ ¹ß»ýÇÏÁö ¾Ê¾Æ¾ß Çϸç, 6) ÁÖ°£ ¹× ¾ß°£ µ¿¾È
Áö¼ÓÀûÀÎ ¿äÀÚÁ¦ÀÇ À¯Áö°¡ °¡´ÉÇÏ¿©¾ß ÇÑ´Ù´Â °ÍÀÌ´Ù. ÀÌµé ³ª¿­µÈ Á¶°Çµé Áß ÃæºÐÇÑ ¹æ±¤
¿ëÀû°ú ³·Àº Ã游³»¾ÐÀº À¯¸®µÈ ÀåºÐÀýÀÇ °ü»ó±¸Á¶¸¦ ¾ø¾Ú(detubularization)À¸·Î½á ¾òÀ» ¼ö
ÀÖ¾ú°í, ¹æ±¤¿ä°ü¿ª·ù´Â ¹æ±¤°ú ¿ä°üÀÇ ¹®Çսà anti-reflux mechanismÀ» ÀÌ¿ëÇÔÀ¸·Î½á ¸·À»
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µé¾îÁø »õ·Î¿î ¹æ±¤À» ÀÚ½ÅÀÇ ¿äµµ¿¡ ¿¬°á½ÃÄÑ ÁÜÀ¸·Î½á, Á¤»óÀûÀÎ ¹è´¢¸¦ À̸¦ ¼ö ÀÖ¾î ȯ
ÀÚÀÇ »îÀÇ ÁúÀ» ³ôÀÏ ¼ö ÀÖ´Ù. ±×·¯³ª ¹æ±¤´ëÄ¡¼úÀ» ½ÃÇà ¹ÞÀº ȯÀÚ Áß¿¡´Â ¿ä½Ç±Ý, ¾àÇÑ ¹è
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½ÃÇà ¹ÞÀº ȯÀÚ¿¡¼­ÀÇ Á¤È®ÇÑ ¹è´¢±âÀü°ú ¹è´¢Àå¾ÖÀÇ ¿øÀÎÀº ¾ÆÁ÷ ¿ÏÀüÈ÷ Á¤¸³µÇÁö ¾ÊÀº ½Ç
Á¤ÀÌ´Ù. ÀÌ¿¡ º» ±³½Ç¿¡¼­´Â ÀÓ»óÀû, ¿ä¿ªµ¿ÇÐÀû, ¹æ»ç¼±ÇÐÀû °üÂûÀ» ÅëÇÏ¿© ¹æ±¤´ëÄ¡¼úÀ»
½ÃÇà¹ÞÀº ȯÀÚÀÇ ¹è´¢ ¾ç»ó ¹× ¹è´¢Àå¾ÖÀÇ ¿øÀÎÀ» ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù.

Purpose : We evaluated voiding patterns and voiding dysfunction after orthotopic
bladder substitution in patients with bladder cancer.
Materials and Methods : We examined a total of 40 male patients of whom 25 had
undergone an ileocolic and 15 had undergone an ileal neobladder. We interviewed the
patients and obtained 3-day voiding diary in all patients and performed urodynamic
study and voiding cystourethrography.
Results : When a good voider is defined as the patient with maximum flow rate of 15
§¢/sec or more and a poor voider is less than 15§¢/sec, mean maximum 1in good
voiders was 20.4¡¾4.2§¢/sec compared with 8.2¡¾3.1§¢/sec in poor voiders. Maximum
bladder capacity, vesical opening pressure, and vesical pressure at the maximum flow
rate were not different significantly between the two groups. All patients voided by
abdominal straining and relaxing the pelvic floor musculature in pressure-flow study.
However, voiding patterns revealed differences between good and poor voiders. In good
voiders, a single long-lasting abdominal straining achieved a smooth voiding, while in
poor voiders, short-lasting frequent abdominal strainings resulted in interrupted and
obstructive urine flow. Good continence during day and night was achieved in 90.6%
and 81.3% of the good voiders and 87.5% and 87.5% of the poor voiders. The maximum
urethral closure pressure and the functional urethral length decreased in incontinent
patients. Voiding cystourethrography revealed that the reservoir was symmetric and its
outlet was well funnelled and wide open at the most dependent portion of the reservoir
in good voiders. However, in poor voiders, the reservoir revealed asymmetric
configuration and its outlet did not funnel or deviated from its caudal location.
Conclusions : Neobladder patients void by abdominal straining in coordination with the
relaxation of pelvic floor musculature. Correct location of the neobladder outlet, minimum
injury to the urethral anastomosis, and maximum preservation of the proximal urethra
are required to the neobladder patients to obtain good voiding and continence.

Å°¿öµå

Orthotopic bladder substitution; Voiding pattern; Voiding dysfunction;

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