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Abstract

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Purpose : There is no agreement in management of ureteropelvic junction
obstruction(UPJO) found in neonatal period. We report our clinical results of newborns
with UPJO who had been managed with our fixed protocol prospectively.
Materials and Methods : According to our protocol, we performed ultrasonography and
MAG-3 scan to 45 neonatal UPJO patients at 1, 3, 6 month of age. The patients were
divided into three groups, Group ¥°(T1/2>20min, RF<35%), Group ¥±(T1/2>20min,
RF>35%) and Group ¥²(T1/2<20min, RF>35%) according to the results of MAG-3 renal
scan. The patients received pyeloplasty when belonged to Group ¥° on follow-up renal
scan or progression of hydronephrosis on ultrasonography.
Results : At one month of age, 5 patients belonged to Group ¥°, 13 patients to Group
¥± and 27 patients to Group ¥². In Group ¥°, we performed the operation to all five
patients within three month of age. Thirteen patients of Group ¥± showed deterioration
of renal function in 3, improvement of renal excretion in 3 and no change in 7 patients
within 6 month follow-up respectively. However operations were performed in 10
patients within 6 month of age. The reasons for operation in Group ¥± were as follows:
the deteriorated renal function in 3, progressed or severe hydronephrosis in 4, and,
urinary tract infection in 3 patients. All 27 patients of Group ¥² showed no deterioration
of renal function and no significant obstruction on follow-up studies. Except one patient
with recurrent UTI, all of the operated cases have maintained good renal function and
nonoperative cases also have shown good renal function until one year old.
Conclusions : By our management protocol we could choose appropriately the cases
which required early intervention or observation without Impairment of renal function in
neonatal UPJO patients.

Å°¿öµå

Neonatal; Ureteropelvic junction obstruction; Pyeloplasty;

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