전립선비대증 환자에서 TURP, ILC, TUNA 및 TEAP 시술의 효과와 안전성의 비교연구
Comparative Study on the Treatment Outcome and Safety of TURP, ILC, TUNA and TEAP for Patients with Benign Prostatic Hyperplasia
김택상, 최성, 류현열, 안정환, 장진호, 조문환,
소속 상세정보
김택상 ( Kim Taek-Sang )
고신대학교 의과대학 비뇨기과학교실
최성 ( Choi Seong )
고신대학교 의과대학 비뇨기과학교실
류현열 ( Rhew Hyun-Yul )
고신대학교 의과대학 비뇨기과학교실
안정환 ( Ahn Jung-Hwan )
고신대학교 의과대학 비뇨기과학교실
장진호 ( Jang Jin-Ho )
고신대학교 의과대학 비뇨기과학교실
조문환 ( Cho Moon-Hwan )
고신대학교 의과대학 비뇨기과학교실
KMID : 0358320060470010013
Abstract
Purpose: We wanted to compare the treatment outcome, safety, efficacy and complications of transurethral resection of the prostate(TURP), interstitial laser coagulation(ILC), transurethral needle ablation(TUNA) and transurethral ethanol ablation of the prostate(TEAP) for the treatment of benign prostatic hyperplasia(BPH).
Materials and Methods: In this prospective, randomized study, a total of 403 patients with symptomatic BPH were treated by TURP, ILC, TUNA or TEAP from January 1998 to December 2002. ILC was performed using the Indigo 830e LaserOpticTM System with a specially designed interstitial thermotherapy light guide, TUNA was performed using the VidaMed TUNA System and TEAP was performed using the ProstajectTM device. The treatment outcomes were evaluated at 3 months, 6 months and 1 year with the International Prostate Symptom Score(IPSS), the prostate volume, the maximal urinary flow rate(Qmax), the post-void residual urine(PVR), and the quality of life(QoL) assessment score.
Results: All the patients in the four groups showed significant improvement for all the parameters. After 1 year, the four groups showed significant improvement in the clinical and voiding parameters(IPSS, Qmax, PVR, prostate volume and QoL). Our results did not show significant differences in the IPSS, prostate volume and QoL among the four groups. However, the TURP group showed a higher Qmax, and the TEAP group showed a less reduced prostate volume than the other groups during the follow-up period(p＜0.05). The period of hospital admission showed no significant difference between the ILC, TUNA and TEAP groups, but the TURP group showed a longer hospital admission period compared to the other groups. The TURP group was markedly associated with more complications than the other groups.
Conclusions: These early results indicate that ILC, TUNA and TEAP are safe, effective and useful alternative therapies to TURP for the patients with symptomatic BPH. (Korean J Urol 2006;47:13-19)
키워드
Treatment outcome;Safety;Benign prostatic hyperplasia
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