표재성 방광암에서 종양 형태의 예후적 의의
Prognostic Significance of the Tumor Configuration in Superficial Bladder Tumor
권순우, 박창면, 김한권, 강길현, 송재석, 박종연,
소속 상세정보
권순우 ( Kwon Soonoo )
울산대학교 의과대학 강릉아산병원 비뇨기과학교실
박창면 ( Park Chang-Myun )
울산대학교 의과대학 강릉아산병원 비뇨기과학교실
김한권 ( Kim Han-Gwun )
울산대학교 의과대학 강릉아산병원 비뇨기과학교실
강길현 ( Kang Gil-Hyun )
울산대학교 의과대학 강릉아산병원 진단병리과
송재석 ( Song Jae-Seok )
관동대학교 의과대학 예방의학교실
박종연 ( Park Jong-Yeon )
울산대학교 의과대학 강릉아산병원 비뇨기과학교실
KMID : 0358320060470030237
Abstract
Purpose: The prognostic factors for superficial bladder tumor that affect tumor recurrence and progression have been studied for many years. They are stage, grade, size, multiplicity, microvessel invasion and etc. This study was performed to evaluate the influence of the tumor configuration on predicting its progression and recurrence.
Materials and Methods: 128 patients who initially presented with superficial bladder tumor(pTis, pTa and pT1) were retrospectively analyzed according to many factors such as stage, grade, size, multiplicity, microvessel invasion and tumor configuration for tumor progression and recurrence after primary transurethral resection.
Results: 48 patients(37.5%) experienced recurrent disease and 20 patients (15.6%) had progressive disease. The absence of stalk and microvessel invasion were the statistically significant factors for recurrence. Only microvessel invasion was a significant prognostic factor for progression.
Conclusion: Only two factors, i.e., the absence of tumor stalk and microvessel invasion, were significant prognostic factors for tumor recurrence. Only microvessel invasion was a significant prognostic factor for tumor progression. When tumors are microvessel invasion positive without stalk after primary transurethral resection, these patients might then benefit from being treated with a more aggressive therapeutic modality. (Korean J Urol 2006;47:237-243)
키워드
Tumor configuration;Prognostic factor;Bladder tumor
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