양측 신경보존 근치적 후치골 전립선적출술 후 발기능의 회복에 영향을 미치는 인자
Predictive Factor to Regain Erectile Function after Bilateral Nerve Sparing Radical Retropubic Prostatectomy in Korean Men
장인호, 한병규, 변석수, 이상은, 홍성규, 한준현, 유지형, 정성진,
소속 상세정보
장인호 ( Chang In-Ho )
분당서울대학교병원 비뇨기과
한병규 ( Han Byoung-Kyu )
분당서울대학교병원 비뇨기과
변석수 ( Byun Seok-Soo )
분당서울대학교병원 비뇨기과
이상은 ( Lee Sang-Eun )
분당서울대학교병원 비뇨기과
홍성규 ( Hong Sung-Kyu )
분당서울대학교병원 비뇨기과
한준현 ( Han Jun-Hyun )
분당서울대학교병원 비뇨기과
유지형 ( Yu Ji-Hyeong )
분당서울대학교병원 비뇨기과
정성진 ( Jeong Seong-Jin )
분당서울대학교병원 비뇨기과
KMID : 0358320070480030283
Abstract
Purpose: To investigate the significance of various preoperative factors with regard to postoperative erectile function in Korean men undergoing a bilateral nerve sparing radical retropubic prostatectomy(BNSRRP), using the validated Korean version of the International Index of Erectile Function (IIEF-5).
Materials & Methods: Between March 2004 and March 2005, 83 consecutive patients, who underwent a BNSRRP, with preoperative IIEF-5 scores greater than 13, were retrospectively analyzed. All patients were asked to answer the IIEF-5 questionnaire during the preoperative period and 1 year postoperatively. The responses were stratified on the basis of the clinical characteristics and the preoperative predictive factors for regaining a normal erectile function(NEF: IIEF-5 score≥18) investigated.
Results: At the baseline, 56 patients(67.5%) had NEF. At the 1 year follow-up after the BNSRRP, 58(70.5%) patients reported a return of a sufficient erection for sexual intercourse, with or without oral phosphodiesterase type 5(PDE5) inhibitors, but 37(44.6%) patients regained a NEF. Of these 37 patients, 15(40.5%) were able to spontaneously regain a NEF, but 22(59.5%) needed the help of oral PDE5 inhibitors. When the patients were divided according to postoperative NEF and erectile dysfunction(ED: 14≤IIEF-5 score＜18), the preoperative IIEF-5 score was the only significant factor for predicting postoperative NEF after a BNSRRP in univariate(p=0.018) and multivariate analyses[p=0.030, odds ratio: 3.482, 95% confidence interval(CI): 1.125-10.774]. Changes in the IIEF-5 score after a BNSRRP significantly decreased for those with preoperative NEF compared with ED(-6.1±5.24 vs. -9.1±7.34, p=0.039).
Conclusion: Our data indicated that preoperative erectile function, as assessed using the IIEF-5 questionnaire, was an independent variable for predicting the recovery of erectile function after a BNSRRP when performed in Korean men.(Korean J Urol 2007;48:283-290)
키워드
Prostate cancer;Prostatectomy;Erectile dysfunction
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