경요도전립선절제술 1년 후 전립선특이항원 변화
Changes in the Serum Prostate-specific Antigen Level One Year after Transurethral Resection of the Prostate
정승일, 윤철웅, 강택원, 권동득, 박광성, 류수방,
소속 상세정보
정승일 ( Jung Seung-Il )
전남대학교 의과대학 비뇨기과학교실
윤철웅 ( Youn Chul-Woong )
전남대학교 의과대학 비뇨기과학교실
강택원 ( Kang Taek-Won )
전남대학교 의과대학 비뇨기과학교실
권동득 ( Kwon Dong-Deuk )
전남대학교 의과대학 비뇨기과학교실
박광성 ( Park Kwang-Sung )
전남대학교 의과대학 비뇨기과학교실
류수방 ( Ryu Soo-Bang )
전남대학교 의과대학 비뇨기과학교실
KMID : 0358320070480070691
Abstract
Purpose: We wanted to investigate how transurethral resection of the prostate(TURP), for treating patients with benign prostate hyperplasia(BPH), affected the serum prostate-specific antigen(PSA) levels. M
Materials & Methods: The serum PSA levels were measured before and 12 months after operation in 57 patients who underwent TURP for BPH. The total prostate weight, as measured by transurethral ultrasonography (TRUS), and the weight of the surgical specimen were examined in relation to the pretreatment PSA value and the changes in the PSA levels after the operation.
Results: The preoperative mean PSA density was 0.10±0.08ng/ml/cc. The postoperative serum PSA levels were decreased significantly after TURP (p=0.002). Removal of 1g of BPH tissue reduced the serum PSA levels by an average of 0.22±0.4ng/ml. The changes in the serum PSA level one year after TURP correlated with the resected chip weights[Y=0.406+0.176x (r=0.526, p＜0.05)].
Conclusion: TURP caused a long term decrease in the serum PSA level. One year after TURP, the PSA levels should be expected to decrease according to the resected chip weights.(Korean J Urol 2007;48:691-695)
키워드
Benign prostatic hyperplasia;Transurethral resection of prostate;Prostate-specific antigen
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