전립선비대증이 있는 환자에서 대사증후군의 의미
The Meaning of Metabolic Syndrome X in Patients Suffering with Benign Prostatic Hyperplasia
박정선, 박종관,
소속 상세정보
박정선 ( Park Jung-Sun )
전북대학교 의과대학 비뇨기과학교실
박종관 ( Park Jong-Kwan )
전북대학교 의과대학 비뇨기과학교실
KMID : 0358320070480070696
Abstract
Purpose: We wanted to evaluate if metabolic syndrome X affects voiding symptoms and erectile function in those patients suffering with benign prostatic hyperplasia(BPH).
Materials & Methods: Between January 2003 and May 2006, we analyzed 68 patients suffering with both BPH and metabolic syndrome X and 112 patients suffering with BPH, but not metabolic syndrome as controls. The diagnosis of metabolic syndrome was made according to the recent consensus report of the National Cholesterol Education Program’s Third Adult Treatment Panel. The blood pressure, obesity, maximal flow rate, residual volume, International Prostate Symptom Score(IPSS), and the International Index of Erectile Function(IIEF) were all measured. The biochemical analyses included determining the levels of serum glucose, total cholesterol, triglycerides, low-density lipoprotein cholesterol(LDL-C), high-density lipoprotein cholesterol(HDL-C) and prostate-specific antigen (PSA). The total prostate volume and transitional zone volume were measured via transrectal ultrasound. Statistical analysis was performed by using Student’s t-test.
Results: There were statistical differences between the two groups with respect to total cholesterol(p=0.045), triglycerides(p＜0.001), HDL-C(p＜ 0.001), glucose(p＜0.001), blood pressure(p＜0.001) and obesity(p＜0.001), respectively. However, there was no significant difference on comparison of the total prostate volume and transitional zone volume, the maximal flow rate, the residual volume, IPSS, IIEF, PSA and LDL-C.
Conclusion: The results of this study suggest that BPH patients with metabolic syndrome X have higher total cholesterol, triglycerides, glucose, blood pressure and obesity, and lower HDL-C. Yet there was no significant difference in the voiding symptoms and erectile function between the patients with BPH who had or didn’t have metabolic syndrome X. (Korean J Urol 2007;48:696-700)
키워드
Benign prostatic hyperplasia;Metabolic syndrome X;Erectile dysfunction
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