Estramustine Phosphate 투여 중지 후 전립선특이항원의 급격한 감소와 증상의 호전을 보인 호르몬 불응성 전립선암 환자
Dramatic Decline of PSA and Symptom Improvement after Estramustine Withdrawal in a Hormone-refractory Prostate Cancer Patient
모교익, 김기호, 서영진, 이경섭,
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모교익 ( Mo Kyo-Ik )
동국대학교 의과대학 비뇨기과학교실
김기호 ( Kim Ki-Ho )
동국대학교 의과대학 비뇨기과학교실
서영진 ( Seo Young-Jin )
동국대학교 의과대학 비뇨기과학교실
이경섭 ( Lee Kyung-Seop )
동국대학교 의과대학 비뇨기과학교실
KMID : 0358320070480070751
Abstract
In some patients with prostate cancer and who manifest disease progression during maximal androgen blockade(MAB) therapy, discontinuation of antiandrogen treatment might result in a significant fall in the level of serum prostate-specific antigen(PSA), and this is often correlated with clinical improvement(antiandrogen withdrawal syndrome). However, a decline in the PSA level after the withdrawal of estramustine phosphate is extremely rare. We report here on a case of dramatic decline in the PSA level after withdrawal of estramustine phosphate in a patient with hormone refractory prostate cancer. (Korean J Urol 2007;48:751-753)
키워드
Prostate cancer;Estramustine;Chemotherapy
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