신세포암 환자의 추적관찰을 위한 FDG-양전자방출단층촬영의 임상적 역할
Clinical Role of F-18 Fluorodeoxyglucose Positron Emission Tomography for Follow-up of Patients with Renal Cell Carcinoma
김건훈, 천기정, 이현무, 조문기,
소속 상세정보
김건훈 ( Kim Geon-Hun )
원자력병원 비뇨기과
천기정 ( Cheon Gi-Jeong )
원자력의학원 핵의학연구실
이현무 ( Lee Hyun-Moo )
성균관대학교 의과대학 비뇨기과학교실
조문기 ( Jo Moon-Ki )
원자력병원 비뇨기과
KMID : 0358320070480080767
Abstract
Purpose: To evaluate the role of [18F]fluorodeoxyglucose-positron emission tomography(FDG-PET) for the follow-up of patients with a renal cell carcinoma(RCC), and compare FDG-PET with conventional imaging modalities, including computerized tomography(CT), chest PA, bone scan and brain magnetic resonance imaging(MRI).
Materials and Methods: FDG-PET and conventional imaging techniques, includingCT, chest PA, bone scan and brain MRI, were performed on 69 patients who had undergone a radical nephrectomy and/or metastatectomy, with a final pathological diagnosis of a RCC. The final diagnoses of recurrences/metastases were established from the histopathological or clinical findings.
Results: Recurrences and metastases were present at 47 sites(34 patients). The results of FDG-PET were true positive and false negative in 44 and 3 of the 47 sites, respectively. The results of conventional imaging techniques were true positive and false negative in 40 and 7 of the 47 sites, respectively. The results of FDG-PET were true negative and false positive in 34 and 1 of the 35 patients, respectively. The results of conventional imaging techniques were true negative and false positive in 30 and 5 of the 35 patients, respectively. Therefore, FDG-PET was more sensitive, specific and accurate than conventional imaging techniques for the follow-up of patients with a RCC.
Conclusions: FDG-PET accurately detected the postoperative recurrences and metastases in patients with a RCC. FDG-PET may have a role in the follow-up of patients with a RCC.
키워드
18F fluorodeoxyglucose; Positron emission tomography; Renal cell carcinoma
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