In Vitro Retrieval of Epididymal Sperm: An Analysis of 11 Years of Cumulative Data
김진수, 김성진, 한혁동,
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김진수 ( Kim Jin-Soo )
연세대학교 원주의과대학 비뇨기과학교실
김성진 ( Kim Sung-Jin )
연세대학교 원주의과대학 비뇨기과학교실
한혁동 ( Han Hyuk-Dong )
연세대학교 원주의과대학 산부인과학교실
KMID : 0358320070480080843
Abstract
Purpose: To evaluate the efficacy of in vitroretrieval of epididymal sperm for the induction of pregnancy in patients with post-testicular causes of infertility, and assess the sperm distribution within the epididymis of these patients.
Materials and Methods: Analyses of the sperm count and motility of sperm retrieved from the detached epididymis, and of the resulting fertilization and pregnancy outcomes were conducted. A total 62 infertile couples, due to post-testicular male causes, had sperm retrieved from the epididymis. The sperm count and motility, as well as the fertilization and pregnancy rates, were measured.
Results: Epididymal sperm was retrieved from 60 males with post-testicular infertility. The average sperm concentration and motility of the sperm after sperm preparation were 43.0x106/ml and 25%, respectively. The clinical pregnancy rate per cycle was 57.9%(11/19) with in vitro fertilization(IVF), 39.0%(16/41) with intracytoplasmic sperm injection(ICSI) using fresh epididymal sperm, and 42.9%(27/63) with ICSI using frozen epididymal sperm.
Conclusions: The in vitro retrieval of epididymal sperm is recommended as a simple and effective method to obtain viable sperm from infertile patients with obstructive azoospermia or sperm excretion disorders.
키워드
Epididymal sperm retrieval; Male infertility; Azoospermia
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