가토에서 Histoacrylⓡ과 Lipiodol 혼합물을 이용한 신동맥 색전술의 유용성
Efficacy of Renal Artery Embolization using a Mixture of Histoacrylⓡ and Lipiodol in a Rabbit Model
이강훈, 김현우, 조수연, 박덕진, 윤병일, 김선욱, 권동일, 백문희,
소속 상세정보
이강훈 ( Lee Kang-Hoon )
가톨릭대학교 의과대학 비뇨기과학교실
김현우 ( Kim Hyun-Woo )
가톨릭대학교 의과대학 비뇨기과학교실
조수연 ( Cho Soo-Yeun )
가톨릭대학교 의과대학 비뇨기과학교실
박덕진 ( Park Duk-Jin )
가톨릭대학교 의과대학 비뇨기과학교실
윤병일 ( Yoon Byung-Il )
가톨릭대학교 의과대학 비뇨기과학교실
김선욱 ( Kim Sun-Wook )
가톨릭대학교 의과대학 비뇨기과학교실
권동일 ( Gwon Dong-Il )
가톨릭대학교 의과대학 방사선과학교실
백문희 ( Paik Moon-Hee )
가톨릭대학교 의과대학 방사선과학교실
KMID : 0358320070480090903
Abstract
Purpose:We wanted to evaluate the efficacy and computed tomography (CT) findings of renal artery embolization with using a mixture of Histoacrylⓡ and lipiodol in rabbit depending on the mixture proportions and the temporal course.
Materials and Methods:Eighteen rabbits were equally divided into two groups:group A received a 1:3 mixture and group B received a 1:5 mixture of Histoacrylⓡ and lipiodol. We subdivided each group as follows: the 1-day group, the 10-day group and the 20-day group according to the elapsed days after embolization, respectively. As a result, the experimental groups were composed of six subgroups. Afterright renal artery embolizations, plain abdominal radiographs were obtained from all the rabbits.
On the first day, the 10th day and the 20th day after embolization, abdominal CT was performed in each subgroup.
Results:On the post-embolization radiographs, the embolic casts were formed only at the main or segmental renal arteries in 7 cases of group A. On the other hand, the embolic casts were formed at the entire arterial
trees in two cases of group A and all the cases of group B. On the precontrast- enhanced CT scans, there were radiopaque densities of embolic casts, residual lipiodol flecks and calcifications in the embolized kidneys.
On the contrast-enhanced CT scans, global perfusion defects of the kidneys were noted in 17 rabbits. The cortical rim signs were noted in all rabbits of the 10-day and 20-day groups, except for one rabbit.
Conclusions:The mixture of Histoacrylⓡ and lipiodol is effective for renal artery embolization. The CT findings of the embolized kidneys are characteristic depending on the mixture proportions of the embolic agents and the temporal courses. (Korean J Urol 2007;48:903-909)
키워드
Renal artery;Therapeutic embolization;Tomography
원문 및 링크아웃 정보
등재저널 정보