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A Primary Large Cell Neuroendocrine Carcinoma of the Urinary Bladder in a 19-year-old Man
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±ÇÈÖ¾È ( Kwon Whi-An )
Chungbuk National University
ÇÏÀ±¼® ( Ha Yun-Sok )
Chungbuk National University
ÀÌ¿ÁÁØ ( Lee Ok-Jun )
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±è¿ëÁØ ( Kim Yong-June )
Chungbuk National University
À±¼®Áß ( Yun Seok-Joong )
Chungbuk National University
ÀÌ»óö ( Lee Sang-Cheol )
Chungbuk National University
±è¿øÀç ( Kim Wun-Jae )
Chungbuk National University
KMID : 0358320080490070647
Abstract
Primary large cell neuroendocrine carcinomas of the urinary bladder are extremely rare. To date, only six cases of large cell neuroendocrine carcinoma have been reported. We present a case of a 19-year-old man who presented with gross hematuria and who was subsequently found to have a solitary tumor on the dome of the urinary bladder. The patient underwent transurethral resection of the bladder tumor for histological confirmation. A diagnosis of large cell neuroendocrine carcinoma was made based upon immunohistochemical reactivity for synaptophysin and CD56. Based on the pathologic diagnosis, he subsequently had a partial cystectomy. Histologically, the tumor penetrated the perivesical fat. It has now been 6 months since the surgery, and the patient is preparing to receive his 5th cycle of chemotherapy. There is no evidence of tumor recurrence or metastasis.
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Carcinoma;large cell;Neuroendocrine carcinoma;Urinary bladder
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