우연히 발견된 신세포암의 특징
Characteristics of Incidentally Detected Renal Cell Carcinoma
신형오, 김영선, 김경도, 장인호, 이신영, 권용욱, 김태형,
소속 상세정보
신형오 ( Shin Hyung-Oh )
중앙대학교 의과대학 비뇨기과학교실
김영선 ( Kim Young-Sun )
중앙대학교 의과대학 비뇨기과학교실
김경도 ( Kim Kyung-Do )
중앙대학교 의과대학 비뇨기과학교실
장인호 ( Chang In-Ho )
중앙대학교 의과대학 비뇨기과학교실
이신영 ( Lee Shin-Young )
중앙대학교 의과대학 비뇨기과학교실
권용욱 ( Kwon Yong-Wook )
중앙대학교 의과대학 비뇨기과학교실
김태형 ( Kim Tae-Hyoung )
중앙대학교 의과대학 비뇨기과학교실
KMID : 0358320080490080675
Abstract
Purpose: This study compared the clinicopathological features, diagnosis and prognosis of an incidental renal cell carcinoma with those of a symptomatic carcinoma. Materials and
Methods: The medical records of 140 renal cell carcinoma patients at our hospital between 1995 and 2004 were reviewed. The patients were divided into two groups: asymptomatic and symptomatic patients. The patients’ characteristics, radiologic studies, tumor stage, tumor size, nuclear grade, and survival rates were investigated. The data was analyzed using a chi-square test, Student’s t-test and Kaplan-Meier survival curve.
Results: Of the 140 patients 57(41%) were asymptomatic and 83(59%) were symptomatic. The median tumor size was 5.2cm for incidental cancer and 8.1cm for symptomatic cancer. The 5-year cancer specific survival rate was significantly higher for the incidental tumors than the symptomatic tumors(78.9% versus 45.8%). When adjusted for stage, there was no difference in survival in those with stage I to IV disease between the 2 groups. Stage I, II lesions were present in 82.5% of patients in the incidental group and 39.7% in the symptomatic group. In contrast, a stage Ⅲ, Ⅳ lesion was present in 17.5% of the patients in the incidental group compared with 60.3% in the symptomatic group. A higher tumor grade of symptomatic lesions was also noted.
Conclusions: The incidental group showed a significantly lower stage and grade, and a higher 5-year survival rate. This result was attributed to the early detection of renal cell carcinoma before the onset of symptoms. Overall, early detection of renal cell carcinoma using radiologic tools will improve the prognosis of renal cell carcinoma. (Korean J Urol 2008;49: 675-681)
키워드
Incidental;Renal cell carcinoma
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