하부요로증상을 호소하는 전립선비대증 환자에서 Doxazosin의 장기 효과
Long Term Effectiveness of Doxazosin in Men with Lower Urinary Tract Symptoms Suggesting of Benign Prostatic Hyperplasia
최준, 장혁수, 이정오, 한보현,
소속 상세정보
최준 ( Choi Jun )
메리놀병원 비뇨기과
장혁수 ( Chang Hyuk-Soo )
계명대학교 의과대학 비뇨기과학교실
이정오 ( Lee Jeong-Oh )
메리놀병원 비뇨기과
한보현 ( Han Bo-Hyun )
메리놀병원 비뇨기과
KMID : 0358320080490111003
Abstract
Purpose: The aim of this study was to evaluate the efficacy of doxazosin over 6 years in men with benign prostatic hyperplasia (BPH).
Materials and Methods: This retrospective study enrolled 33 patients with symptomatic BPH who were prescribed an alpha-blocker from January 1999 to December 2000. We evaluated the changes of International Prostate Symptom Score (IPSS), maximal flow rate (Qmax), quality of life (QoL) and residual urine volume (RUV) between before and after 6-year of treatment.
Results: The percentages of improvement were 40.2% in total IPSS, 40.6% in obstructive symptom, 39.4% in irritative symptom, 44.7% in QoL, 124.8% in Qmax, 33.5% in RUV (p＜0.05). Three patients (9.1%) experienced acute
urinary retention and BPH-related surgery was performed in 6 patients (18.2%).
Conclusions: Our study revealed that long-term treatment over 6 years with alpha-blocker resulted in significant improvements in the IPSS, QoL, Qmax and RUV.
키워드
Benign prostatic hyperplasia;Doxazosin
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