Pseudomonas aeruginosa에 의한 요로감염의 임상적 특성
The Clinical Features of Complicated Urinary Tract Infections by Pseudomonas aeruginosa
이정우, 임정식, 박승철, 오경재,
소속 상세정보
이정우 ( Lee Jung-Woo )
원광대학교 의과대학 비뇨기과학교실
임정식 ( Rim Joung-Sik )
원광대학교 의과대학 비뇨기과학교실
박승철 ( Park Seung-Chol )
원광대학교 의과대학 비뇨기과학교실
오경재 ( Oh Gyung-Jae )
원광대학교 의과대학 예방의학교실
KMID : 0358320080490121149
Abstract
Purpose: Pseudomonas aeruginosa is an important pathogen in complicated urinary tract infections(UTIs). The aim of this study was to evaluate the isolation rate of Pseudomonas from patients with UTIs and to define the accompanying clinical features.
Materials and Methods: Between January 2000 and December 2006, we retrospectively reviewed the medical records of 170 urology patients with Pseudomonas UTIs. We analyzed the isolation rate of Pseudomonas in patients with UTIs and determined the antibiotic susceptibilities. We also analyzed the clinical features and underlying diseases in patients with Pseudomonas UTIs.
Results: Pseudomonas was cultured in the urine from 234 of 3,470 patients (6.6%) with positive urine cultures. One hundred seventy of 234 patients had underlying urologic disease. Eighty-two patients(48.2%) had indwelling urinary catheters and 34 patients(20.0%) had diabetes. Patients with catheters tended to have febrile UTIs compared to patients without catheters(70.7% vs. 42.0%, respectively). The isolation rate of Pseudomonas increased between 2000 and 2006(2.8% vs. 13.1%, respectively). The sensitivity of Pseudomonas to most antibiotics decreased between 2000 and 2006. Patients with neurogenic disease and catheters were more easily infected with Pseudomonas.
Conclusions: The isolation rate of Pseudomonas in urine cultures is on the rise. Patients with UTIs and catheters, unlike those without, have high fevers. Because the sensitivity of Pseudomonas to antimicrobial agents has decreased, we need to choose appropriate antibiotics through urine cultures and antibiotics sensitivity tests in treating complicated UTIs.
키워드
Urinary tract infections;Pseudomonas aeruginosa;Anti-bacterial agents
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