경회음부와 경직장전립선생검술의 비교
The Comparison between Transperineal and Transrectal Ultrasound-Guided Prostate Needle Biopsy
채윤병, 김용준, 이상철, 김원재, 김동욱, 윤석중,
소속 상세정보
채윤병 ( Chae Yun-Byung )
Chungbuk National University
김용준 ( Kim Yong-June )
Chungbuk National University
이상철 ( Lee Sang-Cheol )
Chungbuk National University
김원재 ( Kim Wun-Jae )
Chungbuk National University
김동욱 ( Kim Tong-Wook )
건국대학교 의과대학 비뇨기과학교실
윤석중 ( Yun Seok-Joong )
Chungbuk National University
KMID : 0358320090500020119
Abstract
Purpose: Prostate biopsy is a conventional method for the detection of prostate cancer in men with suspicious findings. However, there is no universal agreement on which method is the better approach to the prostate, with regard to cancer detection rate and complication rate. In this prospective randomized study, we compared cancer detection rates and complication rates between transperineal (TP) and transrectal (TR) prostate biopsy.
Materials and Methods: Between March 2006 and December 2007, we analyzed 200 Korean men. One hundred patients underwent randomized TP prostate biopsy and 100 patients underwent TR prostate biopsy. All biopsies were extended 12-core biopsies. With both approaches, 12 biopsy specimens were obtained systematically from the peripheral and transitional zones, including the apex, base, and transitional zone. The patient’s subjective pain scale was measured by use of visual analogue scales. Immediately after the biopsy, the pain score was independently recorded by the patients. One week later, various complications were measured by answer note.
Results: The overall cancer detection rate was 22% (22 of 100 patients) with TR prostate biopsy and 29% (29 of 100 patients) with TP prostate biopsy. Considering the prostate cancer detection rate, there were no significant differences between the groups for prostate-specific antigen (PSA), age, body mass index (BMI), and prostate volume. Apart from the cancer detection rate and complication rate, the pain scale, in each different approach, was statistically meaningful.
Conclusions: There were no significant differences in the cancer detection rate or complication rate between TP and TR prostate needle biopsy. However, with regard to pain relief and complication rates, TR prostate needle biopsy is preferable. (Korean J Urol 2009;50:119-124)
키워드
Prostatic neoplasms;Biopsy;Pain measurement
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