만성골반통증후군 환자의 치료에서 Terpene Mixture와 알파차단제의 치료효과 비교: 전향적 연구
Comparison of the Efficacy of a Terpene Mixture and Alpha-Blocker for Treatment of Category III Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Prospective Study
차우헌, 김기호, 서영진,
소속 상세정보
차우헌 ( Cha Woo-Heon )
동국대학교 의과대학 비뇨기과학교실
김기호 ( Kim Ki-Ho )
동국대학교 의과대학 비뇨기과학교실
서영진 ( Seo Young-Jin )
동국대학교 의과대학 비뇨기과학교실
KMID : 0358320090500020148
Abstract
Purpose: The aim of this study was to evaluate the efficacy of a terpene mixture compared with alpha-blocker in patients with chronic pelvic pain syndrome (CPPS).
Materials and Methods: Patients diagnosed with CPPS were included in this study. The patients were randomly placed into three groups. Group 1 was treated with levofloxacin alone (36 patients), group 2 was treated with levofloxacin and alfuzosin (33 patients), and group 3 was treated with levofloxacin and terpene mixture (34 patients) for 8 weeks. The National Institutes of Health Chronic Prostatitis Symptom Index (NIH- CPSI) was evaluated in patients in each group at the beginning of the study and after 8 weeks of treatment.
Results: Pain domain, urinary domain, quality of life domain, and total score on the NIH-CPSI were not significantly different at the initial visit. After treatment with each medication, improvements on the pain domain and total score of the NIH-CPSI were better in group 3 than in group 1 or group 2 (p＜0.05). Improvement on the urinary domain of the NIH-CPSI was better in group 2 than in group 1 or group 3 (p=0.014). Changes in the quality of life domain of the NIH-CPSI were not significant among the three groups.
Conclusions: This study suggests that the terpene mixture and alpha- blockers may have significant benefit for symptomatic relief, especially in the pain and urinary domains, respectively.
키워드
Pelvic pain;Adrenergic alpha-antagonists;Terpenes
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