전립선생검에서 비전형적작은꽈리증식증으로 진단된 환자의 재생검 결과
Prostate Cancer Detection Rate of Rebiopsy in Patients with an Initial Diagnosis of Atypical Small Acinar Proliferation of the Prostate
오정우, 김윤범, 양승옥, 이정기, 김윤정, 정태영, 심홍방,
소속 상세정보
오정우 ( Oh Jung-Woo )
서울보훈병원 비뇨기과
김윤범 ( Kim Yun-Beom )
서울보훈병원 비뇨기과
양승옥 ( Yang Seung-Ok )
서울보훈병원 비뇨기과
이정기 ( Lee Jeong-Ki )
서울보훈병원 비뇨기과
김윤정 ( Kim Yoon-Jung )
서울보훈병원 병리과
정태영 ( Jung Tae-Young )
서울보훈병원 비뇨기과
심홍방 ( Shim Hong-Bang )
서울보훈병원 비뇨기과
KMID : 0358320090500030237
Abstract
Purpose: Atypical small acinar proliferation (ASAP) denotes the presence of suspicious glands with insufficient cytological architecture for a definitive prostate cancer diagnosis. We evaluated the subsequent prostate cancer detection rate of rebiopsy in patients with an initial diagnosis of ASAP.
Materials and Methods: Between January 2003 and December 2006, 1,416 men with suspected prostate cancer underwent a transrectal ultrasound- guided prostate biopsy, and 214 (15.1%) were diagnosed as having ASAP. Ninety-five of the 215 patients underwent at least one more biopsy. We evaluated the cancer detection rates after rebiopsy.
Results: In men with ASAP, 36 patients (37.9%) had prostate cancer. The cancer detection rates of the 1st, 2nd, and 3rd rebiopsies were 30.5%, 23.8%, and 40%, respectively. Mean patient age and prostate-specific antigen did not differ significantly between the prostate cancer and noncancer groups after rebiopsy. Prostate volume, however, was significantly smaller in the cancer group (p＜0.05).
Conclusions: Our results showed a detection rate for prostate cancer of 37.9% after an initial diagnosis of ASAP, which indicates that an initial diagnosis of ASAP mandates rebiopsy.
키워드
Atypical small;acinar;proliferation;Biopsy;Prostatic;neoplasms
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