중년 이후 남성에서 발기부전과 대사증후군의 연관성: 한림 노년연구
Association between Erectile Dysfunction and Metabolic Syndrome in Aging Men: Hallym Aging Study
오재록, 최용준, 김동현, 이성호, 정진영, 장숙랑, 이종욱, 이상곤,
소속 상세정보
오재록 ( Oh Jae-Rock )
한림대학교 의과대학 비뇨기과학교실
최용준 ( Choi Yong-Jun )
한림대학교 의과대학 사회의학교실
김동현 ( Kim Dong-Hyun )
한림대학교 의과대학 사회의학교실
이성호 ( Lee Seong-Ho )
한림대학교 의과대학 비뇨기과학교실
정진영 ( Jeong Jin-Young )
한림대학교 고령사회연구소
장숙랑 ( Jang Soong-Nang )
한림대학교 고령사회연구소
이종욱 ( Lee Chong-Wook )
한림대학교 의과대학 비뇨기과학교실
이상곤 ( Lee Sang-Kon )
한림대학교 의과대학 비뇨기과학교실
KMID : 0358320090500070682
Abstract
Purpose: The aim of this study was to investigate the relationship between erectile dysfunction (ED) and metabolic syndrome (MS) in a population- based cohort study, the Hallym Aging Study (HAS).
Materials and Methods: Among the 1,520 participants in HAS, 278 men aged more than 50 years, who underwent detailed health evaluations, including health-related questionnaires, evaluation of their medical history and various lifestyle factors, as well as clinical measurements, were included in the study. ED and MS were assessed by using a 5-item version of the International Index of Erectile Function (IIEF-5) and the guidelines of the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III), respectively, and the relationship between ED and MS was investigated.
Results: Of the 278 men, 120 (43.2%) had MS. Ninety percent of men with MS and 78.5% of men without MS had ED (p＜0.05), and chi-square analysis revealed significant differences in the rate of MS between groups when stratified by ED severity (p＜0.001). The multivariate logistic regression analysis, with control for age and comorbidities, showed that men with MS were 3 times as likely to have ED as were men without MS. Among the metabolic risk factors, only waist circumference (WC) was significantly associated with the presence and severity of ED (p＜0.05).
Conclusions: The presence of MS was an independent risk factor for ED, and WC was the most significant metabolic risk factor predicting the risk of ED. These results highlight the clinical importance of evaluating ED in patients with MS, especially in patients with abnormal WC.
키워드
Erectile dysfunction; Metabolic syndrome; Risk factor
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