건강증진센터를 방문한 성인 한국 남성에서 대사증후군 관련지표와 소변 중 pH의 상관관계
The Correlation between Metabolic Syndrome and Urinary pH in Adult Korean Men Who Visited a Health Promotion Center
정태성, 양원재, 송윤섭,
소속 상세정보
정태성 ( Jung Tae-Sung )
순천향대학교 의과대학 비뇨기과학교실
양원재 ( Yang Won-Jae )
순천향대학교 의과대학 비뇨기과학교실
송윤섭 ( Song Yun-Seob )
순천향대학교 의과대학 비뇨기과학교실
KMID : 0358320090500070694
Abstract
Purpose: Low urinary pH is a risk factor for uric acid stones, and acidic urine has been described as a renal manifestation of the metabolic syndrome. We evaluated the association between metabolic syndrome and urinary pH in adult Korean men who visited a health promotion center.
Materials and Methods: From 2004 to 2008, a total of 18,513 adult men who visited our health promotion center were enrolled in this study. The relation between urinary pH and various parameters associated with the metabolic syndrome were evaluated.
Results: The average age was 45.6 years (range, 18-95 years), and 4987 men (26.9%) were classified as having the metabolic syndrome. The mean urinary pH of the metabolic syndrome group was 5.91, which was significantly lower than that of the normal group (6.08). In univariate and multivariate analysis, body mass index, serum triglyceride, and blood sugar were negatively correlated with urinary pH (p＜0.05). In multivariate logistic regression analysis, obesity (body mass index ≥25 kg/m2), hypertriglyceridemia (≥150 mg/dl), high fasting glucose (≥110 mg/dl), and low high-density lipoprotein cholesterol (＜45 mg/dl) were the significant factors that predicted low urinary pH (≤5.5).
Conclusions: Metabolic syndrome was related to lower urinary pH in ostensively healthy adult Korean men. Further studies are needed to elucidate the exact mechanism responsible for the lower urinary pH in individuals with the metabolic syndrome.
키워드
Metabolic syndrome X; Obesity; Urinalysis
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