전립선비대증 환자에서 전립선조직 구성성분과 요역동학검사의 변수 및 하부요로증상의 관계
Relationships between Relative Proportion of Tissue Components, Urodynamic Parameters, and Low Urinary Tract Symptoms in Patients with Benign Prostatic Hyperplasia
김현승, 이승욱, 김은경, 조정만, 한규흥, 강정윤, 유탁근,
소속 상세정보
김현승 ( Kim Hyun-Seung )
을지대학교 의과대학 을지병원 비뇨기과학교실
이승욱 ( Lee Seung-Wook )
을지대학교 의과대학 을지병원 비뇨기과학교실
김은경 ( Kim Eun-Kyung )
을지대학교 의과대학 을지대학병원 병리학교실
조정만 ( Cho Jeong-Man )
을지대학교 의과대학 을지병원 비뇨기과학교실
한규흥 ( Han Kyu-Heung )
을지대학교 의과대학 을지병원 비뇨기과학교실
강정윤 ( Kang Jung-Yoon )
을지대학교 의과대학 을지병원 비뇨기과학교실
유탁근 ( Yoo Tag-Keun )
을지대학교 의과대학 을지병원 비뇨기과학교실
KMID : 0358320090500090859
Abstract
Purpose: This study was designed to investigate the relationship between the histological composition of the prostate, preoperative clinical parameters, and the results of transurethral resection of prostate (TURP).
Materials and Methods: A total of 61 patients with benign prostatic hyperplasia (BPH) who had undergone TURP were enrolled retrospectively. Slides were surveyed for relative areas (%) of glandular epithelium (GE), stroma (ST), and smooth muscle (SM) in stroma by performing immunohistochemistry, and the mean outcomes were calculated with a computer-assisted image analyzer (x200).
Results: Total prostate volume was less than 40 ml in 19 patients (group 1), 40 to 80 ml in 23 patients (group 2), and more than 80 ml in 19 patients (group 3). The percentage of SM was significantly greater in group 1 (29.5±4.2%) than in group 3 (23.7±3.2%), but GE and ST did not differ significantly. AG number was significantly higher in group 3 than in the other groups but did not correlate with SM. Improvements in International Prostate Symptom Score, which were similar in each group, were positively correlated with SM.
Conclusions: SM in prostate adenoma is increased in men with a small prostate and may play an important role in lower urinary tract symptoms in small BPH.
키워드
Prostatic hyperplasia;Transurethral resection of prostate
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